. Precisely predicting cancer is crucial for cancer treatment. Gene expression profiles make it possible to analyze patterns between genes and cancers on the genome-wide scale. Gene expression data analysis, however, is confronted with enormous chall...
Computer methods and programs in biomedicine
Nov 23, 2016
BACKGROUND AND OBJECTIVES: Researchers have developed effective methods to index free-text clinical notes into structured database, in which negation detection is a critical but challenging step. In Chinese clinical records, negation detection is par...
Early childhood anxiety disorders are common, impairing, and predictive of anxiety and mood disorders later in childhood. Epidemiological studies over the last decade find that the prevalence of impairing anxiety disorders in preschool children range...
BACKGROUND: The recent pandemic of obesity and the metabolic syndrome (MetS) has led to the realisation that new drug targets are needed to either reduce obesity or the subsequent pathophysiological consequences associated with excess weight gain. Ce...
Journal of pharmacological and toxicological methods
Nov 21, 2016
The arterial blood gas (ABG) test is used to assess gas exchange in the lung, and the acid-base level in the blood. However, it is still unclear whether or not ABG test indexes correlate with paraquat (PQ) poisoning. This study investigates the predi...
Biomechanics and modeling in mechanobiology
Nov 18, 2016
An information-based technique is described for applications in mechanical property imaging of soft biological media under quasi-static loads. We adapted the Autoprogressive method that was originally developed for civil engineering applications for ...
The main purpose of this study is to propose, then analyze, and later test a spectral gradient algorithm for solving a convex minimization problem. The considered problem covers the matrix ℓ2,1-norm regularized least squares which is widely used in m...
In histopathological image analysis, the morphology of histological structures, such as glands and nuclei, has been routinely adopted by pathologists to assess the malignancy degree of adenocarcinomas. Accurate detection and segmentation of these obj...
Distinguishing between accidental and abusive head trauma in children can be difficult, as there is a lack of baseline data for pediatric cranial fracture patterns. A porcine head model has recently been developed and utilized in a series of studies ...
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