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Predicting the conversion from clinically isolated syndrome to multiple sclerosis: An explainable machine learning approach.

Multiple sclerosis and related disorders
INTRODUCTION: Predicting the conversion of clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS) is critical to personalizing treatment planning and benefits for patients. The aim of this study is to develop an explainab...

Predicting post-treatment symptom severity for adults receiving psychological therapy in routine care for generalised anxiety disorder: a machine learning approach.

Psychiatry research
Approximately half of generalised anxiety disorder (GAD) patients do not recover from first-line treatments, and no validated prediction models exist to inform individuals or clinicians of potential treatment benefits. This study aimed to develop and...

Machine learning-based integration develops a stress response stated T cell (Tstr)-related score for predicting outcomes in clear cell renal cell carcinoma.

International immunopharmacology
BACKGROUND: Establishment of a reliable prognostic model and identification of novel biomarkers are urgently needed to develop precise therapy strategies for clear cell renal cell carcinoma (ccRCC). Stress response stated T cells (Tstr) are a new T-c...

Enhancing cross-subject EEG emotion recognition through multi-source manifold metric transfer learning.

Computers in biology and medicine
Transfer learning (TL) has demonstrated its efficacy in addressing the cross-subject domain adaptation challenges in affective brain-computer interfaces (aBCI). However, previous TL methods usually use a stationary distance, such as Euclidean distanc...

An efficient Parkinson's disease detection framework: Leveraging time-frequency representation and AlexNet convolutional neural network.

Computers in biology and medicine
Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting the quality of life of over 10 million individuals worldwide. Early diagnosis is crucial for timely intervention and better patient outcomes. Electroencephalogram (EEG) si...

Using Social Media and Artificial Intelligence to Find Your Purpose.

Creative nursing
These days, the distractions of the digital world often obscure the journey to discover one's purpose. Yet these distractions hold clues to that very purpose. This article explores social media and artificial intelligence (AI) as tools to assist indi...

IMU-Based Real-Time Estimation of Gait Phase Using Multi-Resolution Neural Networks.

Sensors (Basel, Switzerland)
This work presents a real-time gait phase estimator using thigh- and shank-mounted inertial measurement units (IMUs). A multi-rate convolutional neural network (CNN) was trained to estimate gait phase for a dataset of 16 participants walking on an in...

Evaluation of Hand Action Classification Performance Using Machine Learning Based on Signals from Two sEMG Electrodes.

Sensors (Basel, Switzerland)
Classification-based myoelectric control has attracted significant interest in recent years, leading to prosthetic hands with advanced functionality, such as multi-grip hands. Thus far, high classification accuracies have been achieved by increasing ...

Applying Machine Learning for Enhanced MicroRNA Analysis: A Companion Risk Tool for Oral Squamous Cell Carcinoma in Standard Care Incisional Biopsy.

Biomolecules
Machine learning analyses within the realm of oral cancer outcomes are relatively underexplored compared to other cancer types. This study aimed to assess the performance of machine learning algorithms in identifying oral cancer patients, utilizing m...

Aleatoric and epistemic uncertainty extraction of patient-specific deep learning-based dose predictions in LDR prostate brachytherapy.

Physics in medicine and biology
In brachytherapy, deep learning (DL) algorithms have shown the capability of predicting 3D dose volumes. The reliability and accuracy of such methodologies remain under scrutiny for prospective clinical applications. This study aims to establish fast...