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Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature.

Circulation
BACKGROUND: The microvasculature, the smallest blood vessels in the body, has key roles in maintenance of organ health and tumorigenesis. The retinal fundus is a window for human in vivo noninvasive assessment of the microvasculature. Large-scale com...

A deep-learning toolkit for visualization and interpretation of segmented medical images.

Cell reports methods
Generalizability of deep-learning (DL) model performance is not well understood and uses anecdotal assumptions for increasing training data to improve segmentation of medical images. We report statistical methods for visual interpretation of DL model...

Estimating severe fever with thrombocytopenia syndrome transmission using machine learning methods in South Korea.

Scientific reports
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease in China, Japan, and Korea. This study aimed to estimate the monthly SFTS occurrence and the monthly number of SFTS cases in the geographical area in Kore...

Sensing small interaction forces through proprioception.

Scientific reports
Understanding the human motor control strategy during physical interaction tasks is crucial for developing future robots for physical human-robot interaction (pHRI). In physical human-human interaction (pHHI), small interaction forces are known to co...

Machine learning implicates the IL-18 signaling axis in severe asthma.

JCI insight
Asthma is a common disease with profoundly variable natural history and patient morbidity. Heterogeneity has long been appreciated, and much work has focused on identifying subgroups of patients with similar pathobiological underpinnings. Previous st...

Detection of diabetes from whole-body MRI using deep learning.

JCI insight
Obesity is one of the main drivers of type 2 diabetes, but it is not uniformly associated with the disease. The location of fat accumulation is critical for metabolic health. Specific patterns of body fat distribution, such as visceral fat, are close...

Selective identification and localization of indolent and aggressive prostate cancers via CorrSigNIA: an MRI-pathology correlation and deep learning framework.

Medical image analysis
Automated methods for detecting prostate cancer and distinguishing indolent from aggressive disease on Magnetic Resonance Imaging (MRI) could assist in early diagnosis and treatment planning. Existing automated methods of prostate cancer detection mo...

Single-port transaxillary robotic thyroidectomy (START): 200-cases with two-step retraction method.

Surgical endoscopy
BACKGROUND: This study aims to report the results of a pioneering clinical study using the single-port transaxillary robotic thyroidectomy (START) for 200 patients with thyroid tumor and to introduce our novel two-step retraction method.

Improving diagnosing performance for malignant parotid gland tumors using machine learning with multifeatures based on diffusion-weighted magnetic resonance imaging.

NMR in biomedicine
In this study, the performance of machine learning in classifying parotid gland tumors based on diffusion-related features obtained from the parotid gland tumor, the peritumor parotid gland, and the contralateral parotid gland was evaluated. Seventy-...

Coherent false seizure prediction in epilepsy, coincidence or providence?

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Seizure forecasting using machine learning is possible, but the performance is far from ideal, as indicated by many false predictions and low specificity. Here, we examine false and missing alarms of two algorithms on long-term datasets to...