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Analysis of defective pathways and drug repositioning in Multiple Sclerosis via machine learning approaches.

Computers in biology and medicine
BACKGROUND: Although some studies show that there could be a genetic predisposition to develop Multiple Sclerosis (MS), attempts to find genetic signatures related to MS diagnosis and development are extremely rare.

Diagnosing brain tumours by routine blood tests using machine learning.

Scientific reports
Routine blood test results are assumed to contain much more information than is usually recognised even by the most experienced clinicians. Using routine blood tests from 15,176 neurological patients we built a machine learning predictive model for t...

A Dual-Modal Attention-Enhanced Deep Learning Network for Quantification of Parkinson's Disease Characteristics.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
It is well known that most patients with Parkinson's disease (PD) have different degree of movement disorders, such as shuffling, festination and akinetic episodes, which could degenerate the life quality of PD patients. Therefore, it is very useful ...

A trial on artificial neural networks in predicting sex through bone length measurements on the first and fifth phalanges and metatarsals.

Computers in biology and medicine
BACKGROUND: Predicting sex is an important problem in forensic medicine. The femur, patella, mandible and calcaneus bones are frequently used in predicting sex. In our study, we aimed to use the artificial neural network (ANN) technique to predict se...

Classification of Cancer at Prostate MRI: Deep Learning versus Clinical PI-RADS Assessment.

Radiology
Background Men suspected of having clinically significant prostate cancer (sPC) increasingly undergo prostate MRI. The potential of deep learning to provide diagnostic support for human interpretation requires further evaluation. Purpose To compare t...

Attenuation correction using 3D deep convolutional neural network for brain 18F-FDG PET/MR: Comparison with Atlas, ZTE and CT based attenuation correction.

PloS one
One of the main technical challenges of PET/MRI is to achieve an accurate PET attenuation correction (AC) estimation. In current systems, AC is accomplished by generating an MRI-based surrogate computed tomography (CT) from which AC-maps are derived....