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Interpretable noninvasive diagnosis of tuberculous pleural effusion using LGBM and SHAP: development and clinical application of a machine learning model.

PeerJ
BACKGROUND: Tuberculous pleural effusion (TPE) is a prevalent tuberculosis complication, with diagnosis presenting considerable challenges. Timely and precise identification of TPE is vital for effective patient management and prognosis, yet existing...

Shaping the future of medical education: A cross-sectional study on ChatGPT attitude and usage among medical students in Sudan.

PloS one
BACKGROUND: Artificial intelligence (AI) is revolutionizing education globally, yet its adoption in medical education remains inadequately understood. ChatGPT, a generative AI tool, offers promising yet doubtful potential for enhancing academic and c...

Convolutional neural network using magnetic resonance brain imaging to predict outcome from tuberculosis meningitis.

PloS one
INTRODUCTION: Tuberculous meningitis (TBM) leads to high mortality, especially amongst individuals with HIV. Predicting the incidence of disease-related complications is challenging, for which purpose the value of brain magnetic resonance imaging (MR...

Leveraging transformers and explainable AI for Alzheimer's disease interpretability.

PloS one
Alzheimer's disease (AD) is a progressive brain ailment that causes memory loss, cognitive decline, and behavioral changes. It is quite concerning that one in nine adults over the age of 65 have AD. Currently there is almost no cure for AD except ver...

Artificial intelligence and omics-based autoantibody profiling in dementia.

Frontiers in immunology
INTRODUCTION: Dementia is a neurodegenerative syndrome marked by the accumulation of disease-specific proteins and immune dysregulation, including autoimmune mechanisms involving autoantibodies. Current diagnostic methods are often invasive, time-con...

A Real-Time Plasma Concentration Prediction Model for Voriconazole in Elderly Patients via Machine Learning Combined with Population Pharmacokinetics.

Drug design, development and therapy
PURPOSE: Voriconazole (VCZ) is a first-line treatment for invasive fungal disease, characterized by a narrow therapeutic window and significant inter-individual variability. It is primarily metabolized by the liver, the function of which declines wit...

Machine learning model based on survey assessment of sleep quality in chronic obstructive pulmonary disease patients.

PloS one
PURPOSE: The aim is to develop a learning model based on clinical and survey data to assess sleep quality and identify determining factors affecting sleep quality in chronic obstructive pulmonary disease (COPD) patients.

Machine Learning Models to Identify Clinically Significant Anxiety in Short-Term Insomnia Using Accelerometers.

Depression and anxiety
Clinically significant anxiety (CSA) is common in individuals with short-term insomnia. This study aims to explore the relationship between CSA and the subjective and objective parameters of sleep in patients with short-term insomnia and construct ma...

Comprehensive Machine Learning-Based Prediction Model for Delirium Risk in Older Patients with Dementia: Risk Factors Identification.

Clinical interventions in aging
BACKGROUND: Delirium superimposed on dementia (DSD) is a severe complication in older adults with dementia, marked by fluctuating cognition, inattention, and altered consciousness. Detection is challenging due to symptom overlap, yet it contributes t...

Amphetamine use and Parkinson's disease: integration of artificial intelligence prediction, clinical corroboration, and mechanism of action analyses.

PloS one
Parkinson's disease (PD) is an increasingly prevalent neurologic condition for which symptomatic, but not preventative, treatment is available. Drug repurposing is an innovate drug discovery method that uncovers existing therapeutics to treat or prev...