Clinical pharmacology and therapeutics
Dec 19, 2019
Lower clearance of immune checkpoint inhibitors is a predictor of improved overall survival (OS) in patients with advanced cancer. We investigated a novel approach using machine learning to identify a baseline composite cytokine signature via clearan...
PURPOSE: Distinguishing benign nevi from malignant melanoma using current histopathological criteria may be very challenging and is one the most difficult areas in dermatopathology. The goal of this study was to identify proteomic differences, which ...
Early detection of skin cancer is very important and can prevent some skin cancers, such as focal cell carcinoma and melanoma. Although there are several reasons that have bad impacts on the detection precision. Recently, the utilization of image pro...
The Journal of dermatological treatment
Oct 31, 2019
Software systems using artificial intelligence for medical purposes have been developed in recent years. The success of deep neural networks (DNN) in 2012 in the image recognition challenge ImageNet LSVRC 2010 fueled expectations of the potential fo...
Clinical cancer research : an official journal of the American Association for Cancer Research
Oct 21, 2019
PURPOSE: Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select patients for adjuvant immunotherapy and accelerate clinical trial design. We present a pathology-based computational method using a deep neural netwo...
Journal of the European Academy of Dermatology and Venereology : JEADV
Oct 8, 2019
BACKGROUND: Machine learning algorithms achieve expert-level accuracy in skin lesion classification based on clinical images. However, it is not yet shown whether these algorithms could have high accuracy when embedded in a smartphone app, where imag...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Oct 7, 2019
One of the essential tasks in medical image analysis is segmentation and accurate detection of borders. Lesion segmentation in skin images is an essential step in the computerized detection of skin cancer. However, many of the state-of-the-art segmen...
IMPORTANCE: A high proportion of suspicious pigmented skin lesions referred for investigation are benign. Techniques to improve the accuracy of melanoma diagnoses throughout the patient pathway are needed to reduce the pressure on secondary care and ...
IEEE journal of biomedical and health informatics
Sep 23, 2019
Deep learning has been used to analyze and diagnose various skin diseases through medical imaging. However, recent researches show that a well-trained deep learning model may not generalize well to data from different cohorts due to domain shift. Sim...