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Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Feb 3, 2024
Histopathology relies on century-old workflows of formalin fixation, paraffin embedding, sectioning, and staining tissue specimens on glass slides. Despite being robust, this conventional process is slow, labor-intensive, and limited to providing two...
STAR protocols
Feb 2, 2024
Manual curation of bacterial cell detections in microscopy images remains a time-consuming and laborious task. This work offers a comprehensive, step-by-step tutorial on training a support vector machine to autonomously distinguish between good and b...
IEEE transactions on medical imaging
Feb 2, 2024
Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers ( [Formula: see text]). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein,...
Scientific data
Feb 1, 2024
Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors. The ...
Scientific reports
Jan 28, 2024
Staining is a crucial step in histopathology that prepares tissue sections for microscopic examination. Hematoxylin and eosin (H&E) staining, also known as basic or routine staining, is used in 80% of histopathology slides worldwide. To enhance the h...
Nature methods
Jan 18, 2024
The development of high-resolution microscopes has made it possible to investigate cellular processes in 3D and over time. However, observing fast cellular dynamics remains challenging because of photobleaching and phototoxicity. Here we report the i...
Nature methods
Jan 2, 2024
Light-sheet microscopes enable rapid high-resolution imaging of biological specimens; however, biological processes span spatiotemporal scales. Moreover, long-term phenotypes are often instigated by rare or fleeting biological events that are difficu...
Computers in biology and medicine
Dec 28, 2023
The diagnosis of kidney disease often involves analysing urine sediment particles. Traditionally, urinalysis was performed manually by collecting urine samples and using a centrifuge, which was prone to manual errors and relied on labour-intensive pr...
Physics in medicine and biology
Dec 12, 2023
. Ultrasound localization microscopy (ULM) enables microvascular reconstruction by localizing microbubbles (MBs). Although ULM can obtain microvascular images that are beyond the ultimate resolution of the ultrasound (US) diffraction limit, it requir...
Development (Cambridge, England)
Nov 16, 2023
Recent work shows that the developmental potential of progenitor cells in the HH10 chick brain changes rapidly, accompanied by subtle changes in morphology. This demands increased temporal resolution for studies of the brain at this stage, necessitat...