AIMC Topic: Middle Aged

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Urinary Complement proteome strongly linked to diabetic kidney disease progression.

Nature communications
Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...

Explainable illicit drug abuse prediction using hematological differences.

Scientific reports
This study aimed to develop a reliable and explainable predictive model for illicit drug use (IDU). The model uses a machine learning (ML) algorithm to predict IDU using hematological differences between illicit drug users (IDUr) and non-users (n-IDU...

Quantitative image analysis of the extracellular matrix of esophageal squamous cell carcinoma and high grade dysplasia via two-photon microscopy.

Scientific reports
Squamous cell carcinoma (SCC) and high-grade dysplasia (HGD) are two different pathological entities; however, they sometimes share similarities in histological structure depending on the context. Thus, distinguishing between the two may require care...

Phenotype augmentation using generative AI for isocitrate dehydrogenase mutation prediction in glioma.

Scientific reports
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...

Machine Learning-Based Analysis of Lifestyle Risk Factors for Atherosclerotic Cardiovascular Disease: Retrospective Case-Control Study.

JMIR medical informatics
BACKGROUND: The risk of developing atherosclerotic cardiovascular disease (ASCVD) varies among individuals and is related to a variety of lifestyle factors in addition to the presence of chronic diseases.

Belun Sleep Platform versus in-lab polysomnography for obstructive sleep apnea diagnosis.

Sleep & breathing = Schlaf & Atmung
OBJECTIVE: We aimed to compare the Belun Sleep Platform (BSP), an artificial intelligence-driven home sleep testing device, with polysomnography (PSG) for diagnosing obstructive sleep apnea. The BSP analyzes oxygen saturation, heart rate, and acceler...

AI-Assisted identification of sex-specific patterns in diabetic retinopathy using retinal fundus images.

PloS one
Diabetic retinopathy (DR) is a microvascular complication of diabetes that can lead to blindness if left untreated. Regular monitoring is crucial for detecting early signs of referable DR, and the progression to moderate to severe non-proliferative D...

Distribution of interscan measurement error in AI-based 3D MRI analysis of knee cartilage thickness in osteoarthritis.

PloS one
PURPOSE: A novel AI-based 3D analysis system was developed to automatically extract bone and cartilage from MRI data and provide average cartilage thickness. This study aimed to analyze the interscan measurement error of knee cartilage thickness in o...

TRI-PLAN: A deep learning-based automated assessment framework for right heart assessment in transcatheter tricuspid valve replacement planning.

International journal of cardiology
BACKGROUND: Efficient and accurate preoperative assessment of the right-sided heart structural complex (RSHSc) is crucial for planning transcatheter tricuspid valve replacement (TTVR). However, current manual methods remain time-consuming and inconsi...

Multi-modal machine learning classifier for idiopathic pulmonary fibrosis predicts mortality in interstitial lung diseases.

Respiratory investigation
BACKGROUND: Interstitial lung disease (ILD) prognostication incorporates clinical history, pulmonary function testing (PFTs), and chest CT pattern classifications. The machine learning classifier, Fibresolve, includes a model to help detect CT patter...