The intracellular pH (pH) is critical for understanding various pathologies, including brain tumors. While conventional pH measurement through P-MRS suffers from low spatial resolution and long scan times, H-based APT-CEST imaging offers higher resol...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jun 1, 2025
PURPOSE: Automated Whole-Breast Ultrasound (ABUS) has been widely used as an important tool in breast cancer diagnosis due to the ability of this technique to provide complete three-dimensional (3D) images of breasts. To eliminate the risk of misdiag...
Deformable brain templates are an important tool in many neuroimaging analyses. Conditional templates (e.g., age-specific templates) have advantages over single population templates by enabling improved registration accuracy and capturing common proc...
INTRODUCTION: Hip fractures, particularly among the elderly, impose a significant public health burden due to increased morbidity and mortality. Femoral neck fractures, commonly resulting from low-energy falls, can lead to severe complications such a...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
Most lung cancer (LC) patients are diagnosed at advanced stages due to the lack of effective screening tools. This multicenter study analyzes 1043 saliva samples (334 LC cases and 709 non-LC cases) using a novel high-throughput platform for metabolic...
According to the statistics of relevant data, stroke is a relatively common cerebrovascular disease, and its incidence rate is as high as 185/100,000 to 219/100,000. Continuous care can improve the quality of life of stroke patients and reduce the ra...
BACKGROUND: Large Language Models (LLMs) hold promise for clinical decision support, but their real-world performance varies. We compared three leading models (OpenAI's "o1" Large Reasoning Model (LRM), Anthropic's Claude-3.5-Sonnet, and Meta's Llama...
BACKGROUND: Considering the prevalence of Alzheimer's Disease (AD) among the aging population and the limited means of treatment, early detection emerges as a crucial focus area whereas electroencephalography (EEG) provides a promising diagnostic too...
CPT: pharmacometrics & systems pharmacology
Jun 1, 2025
Selective serotonin reuptake inhibitors (SSRIs) are widely used in depression treatment. However, the relationship between treatment efficacy and plasma concentrations remains unclear. We assessed whether the anti-depressive response can be predicted...
BACKGROUND: Endoscopic balloon dilation (EBD) is recognized as a minimally invasive and effective procedure for managing intestinal stenosis in patients with Crohn's disease (CD). It offers an alternative to surgery and has been shown to improve the ...
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