OBJECTIVE: To construct and validate a predictive model for the risk of postoperative constipation in middle-aged and elderly patients with lower limb fractures based on machine learning algorithms, so as to provide decision-making support for clinic...
Clinical heterogeneity among hemodialysis patients necessitates precision medicine approaches transcending conventional single-parameter management. Through machine learning analysis of 1,207 maintenance hemodialysis patients, we developed a novel tw...
Parkinson's disease (PD) is a brain disorder, that affects a person's body movement causing stiffness, shaking and imbalance. Earlier detection of PD is a challenging task for researchers. In this paper, earlier detection of PD is performed using the...
Personal identification of an individual has always been a major concern in forensic science. Reconstruction of the facial profile is considered as one of the final stages in the process of identification. Nevertheless, recent advancements in artific...
Proximal junctional failure (PJF) is a significant mechanical complication following corrective surgery for adult spinal deformity (ASD), often resulting in structural failure at the uppermost instrumented vertebra and necessitating revision surgery....
NPJ primary care respiratory medicine
Nov 20, 2025
OBJECTIVE: This study explored the application of Machine Learning (ML) techniques to cluster patients with suspected sleep apnea (SA), based on clinical-demographic data, with the aim of optimizing diagnostic pathways and enabling more personalized ...
Mitochondrial autophagy (mitophagy) in macrophages is crucial yet poorly understood within the lung adenocarcinoma (LUAD) tumor microenvironment. This study aimed to identify key macrophage mitophagy-related genes and develop a robust prognostic mode...
OBJECTIVES: BMI and age are associated with the risk of osteoporosis (OP). The dynamic facial aging process involves changes in skin, muscle, fat, and facial bone structures, with facial skeletal aging affecting facial contours through volumetric red...
Lactylation is a post-translational modification that can influence the onset and progression of various diseases.However, its role in Idiopathic Pulmonary Fibrosis (IPF) has not been systematically investigated. Single-cell sequencing and bulk RNA s...
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...
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