This study looked at possible targets for hypertrophic cardiomyopathy (HCM), a condition marked by thickening of the ventricular wall, primarily in the left ventricle. We employed differential gene analysis and weighted gene co-expression network ana...
Mitochondrial dysfunction plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study combines bioinformatics analysis with machine learning to elucidate potential key mitochondrial-related genes associated wi...
Journal of pharmaceutical and biomedical analysis
Apr 23, 2025
Mitochondrial dysfunction, a central pathogenic driver of heart failure (HF), underscores the therapeutic imperative to preserve mitochondrial homeostasis. Qishenyiqi dropping pills (QSYQ), a clinically validated traditional Chinese formulation, exhi...
Ischemic stroke (IS) is a leading cause of death and disability worldwide, often associated with immune dysregulation, mitochondrial dysfunction, and altered protein succinylation. This study aimed to identify mitochondrial and succinylation-related ...
The morphology of the mitochondrial network is a major indicator of cellular health and function, with changes often linked to various physiological and pathological conditions. As a result, efficient methods to quickly assess mitochondrial shape in ...
OBJECTIVE: Lung adenocarcinoma (LUAD) continues to be a primary cause of cancer-related mortality globally, highlighting the urgent need for novel insights finto its molecular mechanisms. This study aims to investigate the relationship between gene e...
Alga toxins have recently emerged as environmental risk factors to multiple human health issues. Mitochondrial toxicity is an essential element in the field of ecotoxicology, it is necessary to screen and manage mitochondrial toxicants from common al...
Journal of clinical monitoring and computing
Mar 30, 2025
Monitoring in vivo mitochondrial oxygen tension (mitoPO) enables the measurement of mitochondrial oxygen consumption (mitoVO), providing deeper insights into the skin's mitochondrial environment. However, current mitoVO analysis often relies on manua...
Morphometric analysis of digital images is fundamental to substantiate the visual observations with objective quantitative data suitable for statistical analysis. The recent advances in artificial intelligence (AI) have allowed the development of mac...
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