AIMC Topic: Models, Biological

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Inferring landscape-scale land-use impacts on rivers using data from mesocosm experiments and artificial neural networks.

PloS one
Identifying land-use drivers of changes in river condition is complicated by spatial scale, geomorphological context, land management, and correlations among responding variables such as nutrients and sediments. Furthermore, variations in standard me...

Mechanical characterization of bone anchors used with a bone-attached, parallel robot for skull surgery.

Medical engineering & physics
Bone-attached robots and microstereotactic frames, intended for deep brain stimulation and minimally invasive cochlear implantation, typically attach to a patient's skull via bone anchors. A rigid and reliable link between such devices and the skull ...

Combining computational models, semantic annotations and simulation experiments in a graph database.

Database : the journal of biological databases and curation
Model repositories such as the BioModels Database, the CellML Model Repository or JWS Online are frequently accessed to retrieve computational models of biological systems. However, their storage concepts support only restricted types of queries and ...

Flying over uneven moving terrain based on optic-flow cues without any need for reference frames or accelerometers.

Bioinspiration & biomimetics
Two bio-inspired guidance principles involving no reference frame are presented here and were implemented in a rotorcraft, which was equipped with panoramic optic flow (OF) sensors but (as in flying insects) no accelerometer. To test these two guidan...

A small-scale hyperacute compound eye featuring active eye tremor: application to visual stabilization, target tracking, and short-range odometry.

Bioinspiration & biomimetics
In this study, a miniature artificial compound eye (15 mm in diameter) called the curved artificial compound eye (CurvACE) was endowed for the first time with hyperacuity, using similar micro-movements to those occurring in the fly's compound eye. A ...

Coefficient of Friction Patterns Can Identify Damage in Native and Engineered Cartilage Subjected to Frictional-Shear Stress.

Annals of biomedical engineering
The mechanical loading environment encountered by articular cartilage in situ makes frictional-shear testing an invaluable technique for assessing engineered cartilage. Despite the important information that is gained from this testing, it remains un...

Human Joint Angle Estimation with Inertial Sensors and Validation with A Robot Arm.

IEEE transactions on bio-medical engineering
Traditionally, human movement has been captured primarily by motion capture systems. These systems are costly, require fixed cameras in a controlled environment, and suffer from occlusion. Recently, the availability of low-cost wearable inertial sens...

Merging and scoring molecular interactions utilising existing community standards: tools, use-cases and a case study.

Database : the journal of biological databases and curation
The evidence that two molecules interact in a living cell is often inferred from multiple different experiments. Experimental data is captured in multiple repositories, but there is no simple way to assess the evidence of an interaction occurring in ...

Pharmacokinetics of single and repeat doses of icatibant.

Clinical pharmacology in drug development
PURPOSE: Icatibant is a bradykinin-2 receptor antagonist approved to treat acute hereditary angioedema attacks in adults. To-date, no thorough investigation of the clinical pharmacokinetic (PK) parameters of icatibant and its primary metabolites has ...

On extracting design principles from biology: II. Case study-the effect of knee direction on bipedal robot running efficiency.

Bioinspiration & biomimetics
Comparing the leg of an ostrich to that of a human suggests an important question to legged robot designers: should a robot's leg joint bend in the direction of running ('forwards') or opposite ('backwards')? Biological studies cannot answer this que...