AIMC Topic: Molecular Imaging

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LeukocyteMask: An automated localization and segmentation method for leukocyte in blood smear images using deep neural networks.

Journal of biophotonics
Digital pathology and microscope image analysis is widely used in comprehensive studies of cell morphology. Identification and analysis of leukocytes in blood smear images, acquired from bright field microscope, are vital for diagnosing many diseases...

Breast cancer histopathological image classification using convolutional neural networks with small SE-ResNet module.

PloS one
Although successful detection of malignant tumors from histopathological images largely depends on the long-term experience of radiologists, experts sometimes disagree with their decisions. Computer-aided diagnosis provides a second option for image ...

MALDI-Imaging for Classification of Epithelial Ovarian Cancer Histotypes from a Tissue Microarray Using Machine Learning Methods.

Proteomics. Clinical applications
PURPOSE: Precise histological classification of epithelial ovarian cancer (EOC) has immanent diagnostic and therapeutic consequences, but remains challenging in histological routine. The aim of this pilot study is to examine the potential of matrix-a...

Unsupervised Two-Path Neural Network for Cell Event Detection and Classification Using Spatiotemporal Patterns.

IEEE transactions on medical imaging
Automatic event detection in cell videos is essential for monitoring cell populations in biomedicine. Deep learning methods have advantages over traditional approaches for cell event detection due to their ability to capture more discriminative featu...

Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Machine Learning for Molecular Recognition of Myocardial Infarction.

Analytical chemistry
Lipid profile changes in heart muscle have been previously linked to cardiac ischemia and myocardial infarction, but the spatial distribution of lipids and metabolites in ischemic heart remains to be fully investigated. We performed desorption electr...

Molecular imaging with neural training of identification algorithm (neural network localization identification).

Microscopy research and technique
Superresolution localization microscopy strongly relies on robust identification algorithms for accurate reconstruction of the biological systems it is used to measure. The fields of machine learning and computer vision have provided promising soluti...

Identifying tumor in pancreatic neuroendocrine neoplasms from Ki67 images using transfer learning.

PloS one
The World Health Organization (WHO) has clear guidelines regarding the use of Ki67 index in defining the proliferative rate and assigning grade for pancreatic neuroendocrine tumor (NET). WHO mandates the quantification of Ki67 index by counting at le...

SetSVM: An Approach to Set Classification in Nuclei-Based Cancer Detection.

IEEE journal of biomedical and health informatics
Due to the importance of nuclear structure in cancer diagnosis, several predictive models have been described for diagnosing a wide variety of cancers based on nuclear morphology. In many computer-aided diagnosis (CAD) systems, cancer detection tasks...

Application of Deep Learning in Automated Analysis of Molecular Images in Cancer: A Survey.

Contrast media & molecular imaging
Molecular imaging enables the visualization and quantitative analysis of the alterations of biological procedures at molecular and/or cellular level, which is of great significance for early detection of cancer. In recent years, deep leaning has been...

Nano-topography Enhances Communication in Neural Cells Networks.

Scientific reports
Neural cells are the smallest building blocks of the central and peripheral nervous systems. Information in neural networks and cell-substrate interactions have been heretofore studied separately. Understanding whether surface nano-topography can dir...