AIMC Topic: Molecular Sequence Annotation
Clear Filters Showing 121 to 130 of 260 articles
g:Profiler-a web server for functional interpretation of gene lists (2016 update).
Nucleic acids research
Apr 20, 2016
Functional enrichment analysis is a key step in interpreting gene lists discovered in diverse high-throughput experiments. g:Profiler studies flat and ranked gene lists and finds statistically significant Gene Ontology terms, pathways and other gene ...
Extending gene ontology in the context of extracellular RNA and vesicle communication.
Journal of biomedical semantics
Apr 12, 2016
BACKGROUND: To address the lack of standard terminology to describe extracellular RNA (exRNA) data/metadata, we have launched an inter-community effort to extend the Gene Ontology (GO) with subcellular structure concepts relevant to the exRNA domain....
ICEPO: the ion channel electrophysiology ontology.
Database : the journal of biological databases and curation
Apr 7, 2016
Ion channels are transmembrane proteins that selectively allow ions to flow across the plasma membrane and play key roles in diverse biological processes. A multitude of diseases, called channelopathies, such as epilepsies, muscle paralysis, pain syn...
The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database.
Database : the journal of biological databases and curation
Mar 23, 2016
The Rat Genome Database (RGD;http://rgd.mcw.edu/) provides critical datasets and software tools to a diverse community of rat and non-rat researchers worldwide. To meet the needs of the many users whose research is disease oriented, RGD has created a...
GO annotation in InterPro: why stability does not indicate accuracy in a sea of changing annotations.
Database : the journal of biological databases and curation
Mar 19, 2016
The removal of annotation from biological databases is often perceived as an indicator of erroneous annotation. As a corollary, annotation stability is considered to be a measure of reliability. However, diverse data-driven events can affect the stab...
UniProt-DAAC: domain architecture alignment and classification, a new method for automatic functional annotation in UniProtKB.
Bioinformatics (Oxford, England)
Mar 7, 2016
MOTIVATION: Similarity-based methods have been widely used in order to infer the properties of genes and gene products containing little or no experimental annotation. New approaches that overcome the limitations of methods that rely solely upon sequ...
LedPred: an R/bioconductor package to predict regulatory sequences using support vector machines.
Bioinformatics (Oxford, England)
Dec 1, 2015
UNLABELLED: Supervised classification based on support vector machines (SVMs) has successfully been used for the prediction of cis-regulatory modules (CRMs). However, no integrated tool using such heterogeneous data as position-specific scoring matri...
Lynx: a knowledge base and an analytical workbench for integrative medicine.
Nucleic acids research
Nov 20, 2015
Lynx (http://lynx.ci.uchicago.edu) is a web-based database and a knowledge extraction engine. It supports annotation and analysis of high-throughput experimental data and generation of weighted hypotheses regarding genes and molecular mechanisms cont...
A-DaGO-Fun: an adaptable Gene Ontology semantic similarity-based functional analysis tool.
Bioinformatics (Oxford, England)
Oct 17, 2015
SUMMARY: Gene Ontology (GO) semantic similarity measures are being used for biological knowledge discovery based on GO annotations by integrating biological information contained in the GO structure into data analyses. To empower users to quickly com...
PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain.
Theoretical biology & medical modelling
Sep 22, 2015
BACKGROUND: Despite the unprecedented and increasing amount of data, relatively little progress has been made in molecular characterization of mechanisms underlying Parkinson's disease. In the area of Parkinson's research, there is a pressing need to...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32021
- Neural Networks, Computer 30231
- Algorithms 27405
- Deep Learning 26912
- Artificial Intelligence 24844
- Robotics 13389
- Image Processing, Computer-Assisted 9738
- Retrospective Studies 9346
- Magnetic Resonance Imaging 6347
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4866
- Support Vector Machine 4771
- Computational Biology 4333
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6800
- Sensors (Basel, Switzerland) 4794
- PloS one 4210
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1066
- Nature communications 1047
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 874
- Journal of medical Internet research 864
- Briefings in bioinformatics 853