AIMC Topic: Nanoparticles

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Application of acoustic spectroscopy and neural networks to on-line size measurement of pharmaceutical nanocrystals.

The Journal of the Acoustical Society of America
Acoustic spectroscopy and neural networks (NNs) are applied to on-line real-time measurement of particle size distribution (PSD) during wet milling of pharmaceutical nanocrystals. A method for modeling the relationship between acoustic attenuation sp...

Machine learning algorithms to control concentrations of carbon nanocomplexes in a biological medium via optical absorption spectroscopy: how to choose and what to expect?

Applied optics
A solution of spectroscopic inverse problems, implying determination of target parameters of the research object via analysis of spectra of various origins, is an overly complex task, especially in case of strong variability of the research object. O...

Choline Proline Ionic Liquid-Functionalized FeO@SiO Nanoparticle Magnetic Solid Phase Extraction Coupled with High-Performance Liquid Chromatography for Analysis of Allura Red in Lipstick Sample.

Journal of cosmetic science
A separation/analysis of allura red based on magnetic solid-phase extraction-high-performance liquid chromatography was developed. The extractant was prepared by functionalizing choline proline ionic liquid on FeO@SiO(FeO@SiO@[Ch][Pro]). Infl uences ...

Improvement of solubility and dissolution of ebastine by fabricating phosphatidylcholine/ bile salt bilosomes.

Pakistan journal of pharmaceutical sciences
Although ebastine (EBT) can impede histamine-induced skin allergic reaction and persuade long acting selective H1 receptor antagonistic effects but its poor water solubility circumscribed its clinical application. The main objective of this research ...

Artificial neural networks for the inverse design of nanoparticles with preferential nano-bio behaviors.

The Journal of chemical physics
Safe and efficient use of ultrasmall nanoparticles (NPs) in biomedicine requires numerous independent conditions to be met, including colloidal stability, selectivity for proteins and membranes, binding specificity, and low affinity for plasma protei...

Sustainable manufacturing of sensors onto soft systems using self-coagulating conductive Pickering emulsions.

Science robotics
Compliant sensors based on composite materials are necessary components for geometrically complex systems such as wearable devices or soft robots. Composite materials consisting of polymer matrices and conductive fillers have facilitated the manufact...

Designing nanoparticle release systems for drug-vitamin cancer co-therapy with multiplicative perturbation-theory machine learning (PTML) models.

Nanoscale
Nano-systems for cancer co-therapy including vitamins or vitamin derivatives have showed adequate results to continue with further research studies to better understand them. However, the number of different combinations of drugs, vitamins, nanoparti...

Supervised Machine Learning Algorithms for Evaluation of Solid Lipid Nanoparticles and Particle Size.

Combinatorial chemistry & high throughput screening
AIMS AND OBJECTIVES: Solid Lipid Nanoparticles (SLNs) are pharmaceutical delivery systems that have advantages such as controlled drug release, long-term stability etc. Particle Size (PS) is one of the important criteria of SLNs. These factors affect...

Development and validation of a LC-FL method for the simultaneous determination of doxorubicin and celecoxib in nanoparticulate fixed dose combination (NanoFDC).

Die Pharmazie
An isocratic reversed phase HPLC method for the simultaneous determination of doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination (NanoFDC) was developed and validated. Linearity of the results was demonstrated from...

Silica Cross-Linked Micellar Core--Shell Nanoparticles Encapsulating IR-780 with Strong Bright and Good Biocompatibility for Optical Imaging In Vivo.

Journal of biomedical nanotechnology
IR-780 iodide, a near-infrared (NIR) fluorescent heptamethine dye, has attracted wide attention in the biomedical community. However, hydrophobicity and toxicity severely limit its further biomedical application. Although many successful efforts have...