The aim is to present expert-agreed guidelines for the primary prevention of cardiovasculotoxicity of anticancer therapy as part of the Cardioprotection 2025 Consensus of the Russian Society of Cardiology, the Society of Heart Failure Specialists, th...
Medical oncology (Northwood, London, England)
Dec 26, 2025
Adeno-associated virus (AAV) has emerged as a pivotal vector for cancer gene therapy due to its low immunogenicity, non-pathogenicity, and sustained transgene expression capacity. However, the heterogeneity and complexity of the tumor microenvironmen...
Current treatment options in oncology
Dec 24, 2025
Improved survival in pediatric oncology has highlighted the growing burden of cancer treatment-related cardiotoxicity among survivors of childhood cancers. While the cardiotoxicity of anthracyclines and chest radiation are well documented as major co...
Journal of chemical information and modeling
Dec 23, 2025
Accurate protein subcellular localization (PSL) is essential for proteins to perform their biological functions, whereas protein mis-localization can disrupt cellular processes and contribute to various diseases, particularly cancer. Although spatial...
BACKGROUND: In oncology, early palliative care enhances quality of life and may increase survival; yet, because of resource limitations and overestimation of prognosis, referrals frequently happen late. Due to a shortage of specialised workers, this ...
The integration of diagnostic imaging with radiation therapy (RT) is evolving into a continuous workflow, significantly advancing personalised oncology care. Recent technological innovations, particularly the incorporation of real-time magnetic reson...
Cancer molecular subtype classification is an essential component of precision oncology which provides insights into cancer prognosis and guides targeted therapy. Despite the growing applications of AI for cancer molecular subtype classification, cha...
Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...
Proteomics has become a transformative tool in oncology, offering unique opportunities for early detection, diagnosis, and cancer stratification. By enabling large-scale analysis of protein expression, interactions, and post-translational modificatio...
Janus kinase 3 (JAK3) is a hematopoietic-specific kinase implicated in cytokine signaling and immune dysregulation and has recently been associated with cancer progression. However, selective and potent JAK3 inhibitors remain underdeveloped. In this ...
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