Biomedical materials (Bristol, England)
Nov 7, 2025
Cancer is among the major causes of mortality, responsible for approximately 15% of all deaths worldwide. Despite remarkable progress in modern medicine, it remains a significant global health challenge. Nevertheless, conventional therapies such as c...
PURPOSE: Explore public perceptions and sentiments about cancer screening on social media. The dissemination of misinformation and negative attitudes continue to impede the access of many individuals with perceived risk to cancer screening services d...
Cytotoxic T cells (CD8) play a pivotal role in immunosurveillance by identifying and eliminating tumor cells. However, the onset of CD8 T cell exhaustion, characterized by overexpression of immune checkpoint receptors, impairs their function, allowin...
Journal of computer-aided molecular design
Nov 4, 2025
Evolution has optimized proteins over time by the incorporation of precise and context-specific amino acid substitutions adapted to structural and functional demands. We have reconceptualized this principle using deep learning to engineer monoclonal ...
Mathematical oncology is an interdisciplinary research field where the mathematical sciences meet cancer research. Being situated at the intersection of these two fields makes mathematical oncology highly dynamic, as practicing researchers are incent...
Heterogeneity in cancer is known to be a contributor to the formation of metastatic lesions, poor prognosis, and ultimately undermines therapeutic efficacy. This same tumor heterogeneity is reflected in circulating tumor cells (CTCs) and tumor derive...
PURPOSE: Objectives were to develop a machine learning (ML) model based on electronic health record (EHR) data to predict the risk of vomiting within a 96-hour window after admission to the pediatric oncology and hematopoietic cell transplant (HCT) s...
Accurate detection of somatic variants in tumors is of critical importance and remains challenging. Current methods typically require matched normal samples for reliable detection, which are often unavailable in real-world research and clinical scena...
Cancer diagnosis at an early stage is crucial for improving overall health outcomes. However, existing cancer diagnostic techniques are mostly invasive and tend to identify the disease only in its advanced stages. MicroRNAs (miRNAs), which are small ...
Artificial intelligence (AI) is rapidly revolutionizing the landscape of oncological research and the advancement of personalized clinical interventions. Progress in three interconnected areas, including the development of methods and algorithms for ...
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