Journal of chemical information and modeling
Feb 5, 2021
Solvation free energy is a fundamental property that influences various chemical and biological processes, such as reaction rates, protein folding, drug binding, and bioavailability of drugs. In this work, we present a deep learning method based on g...
Prostate cancer (PCa) is the second most frequently diagnosed cancer among men worldwide, with almost 1.3 million new cases and 360,000 deaths in 2018. As it has been estimated, its mortality will double by 2040, mostly in countries with limited reso...
Egocentric activity recognition in first-person video (FPV) requires fine-grained matching of the camera wearer's action and the objects being operated. The traditional method used for third-person action recognition does not suffice because of (1) t...
Gait patterns are a result of the complex kinematics that enable human two-legged locomotion, and they can reveal a lot about a person's state and health. Analysing them is useful for researchers to get new insights into the course of diseases, and f...
Machine learning has greatly facilitated the analysis of medical data, while the internal operations usually remain intransparent. To better comprehend these opaque procedures, a convolutional neural network for optical coherence tomography image seg...
Viral co-infections occur in COVID-19 patients, potentially impacting disease progression and severity. However, there is currently no dedicated method to identify viral co-infections in patient RNA-seq data. We developed PACIFIC, a deep-learning alg...
A common problem found in real-word medical image classification is the inherent imbalance of the positive and negative patterns in the dataset where positive patterns are usually rare. Moreover, in the classification of multiple classes with neural ...
BACKGROUND: Survival analysis is an important part of cancer studies. In addition to the existing Cox proportional hazards model, deep learning models have recently been proposed in survival prediction, which directly integrates multi-omics data of a...
IEEE journal of biomedical and health informatics
Feb 5, 2021
The high capacity of neural networks allows fitting models to data with high precision, but makes generalization to unseen data a challenge. If a domain shift exists, i.e. differences in image statistics between training and test data, care needs to ...
IEEE journal of biomedical and health informatics
Feb 5, 2021
Mitotic count is an important indicator for assessing the invasiveness of breast cancers. Currently, the number of mitoses is manually counted by pathologists, which is both tedious and time-consuming. To address this situation, we propose a fast and...
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