AIMC Topic: Opioid-Related Disorders

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Understanding Opioid Use Disorder (OUD) using tree-based classifiers.

Drug and alcohol dependence
BACKGROUND: Opioid Use Disorder (OUD), defined as a physical or psychological reliance on opioids, is a public health epidemic. Identifying adults likely to develop OUD can help public health officials in planning effective intervention strategies. T...

Rapid Assessment of Opioid Exposure and Treatment in Cities Through Robotic Collection and Chemical Analysis of Wastewater.

Journal of medical toxicology : official journal of the American College of Medical Toxicology
INTRODUCTION: Accurate data regarding opioid use, overdose, and treatment is important in guiding community efforts at combating the opioid epidemic. Wastewater-based epidemiology (WBE) is a potential method to quantify community-level trends of opio...

Using machine learning to predict opioid misuse among U.S. adolescents.

Preventive medicine
This study evaluated prediction performance of three different machine learning (ML) techniques in predicting opioid misuse among U.S. adolescents. Data were drawn from the 2015-2017 National Survey on Drug Use and Health (N = 41,579 adolescents, age...

Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose.

ACS chemical neuroscience
The United States of America is fighting against one of its worst-ever drug crises. Over 900 people a week die from opioid- or heroin-related overdoses, while millions more suffer from opioid prescription addiction. Recently, drug overdoses caused by...

Development of Machine Learning Algorithms for Prediction of Sustained Postoperative Opioid Prescriptions After Total Hip Arthroplasty.

The Journal of arthroplasty
BACKGROUND: Postoperative recovery after total hip arthroplasty (THA) can lead to the development of prolonged opioid use but there are few tools for predicting this adverse outcome. The purpose of this study is to develop machine learning algorithms...

Natural Language Processing-Identified Problem Opioid Use and Its Associated Health Care Costs.

Journal of pain & palliative care pharmacotherapy
Use of prescription opioids and problems of abuse and addiction have increased over the past decade. Claims-based studies have documented substantial economic burden of opioid abuse. This study utilized electronic health record (EHR) data to identify...

A computational strategy for finding novel targets and therapeutic compounds for opioid dependence.

PloS one
Opioids are widely used for treating different types of pains, but overuse and abuse of prescription opioids have led to opioid epidemic in the United States. Besides analgesic effects, chronic use of opioid can also cause tolerance, dependence, and ...

Detecting Opioid-Related Aberrant Behavior using Natural Language Processing.

AMIA ... Annual Symposium proceedings. AMIA Symposium
The United States is in the midst of a prescription opioid epidemic, with the number of yearly opioid-related overdose deaths increasing almost fourfold since 2000. To more effectively prevent unintentional opioid overdoses, the medical profession re...