AIMC Topic: Organs at Risk

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A deep learning-based auto-segmentation system for organs-at-risk on whole-body computed tomography images for radiation therapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Delineating organs at risk (OARs) on computed tomography (CT) images is an essential step in radiation therapy; however, it is notoriously time-consuming and prone to inter-observer variation. Herein, we report a deep learning...

Deep learning-based auto-segmentation of organs at risk in high-dose rate brachytherapy of cervical cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Delineation of organs at risk (OARs), such as the bladder, rectum and sigmoid, plays an important role in the delivery of optimal absorbed dose to the target owing to the steep gradient in high-dose rate brachytherapy (HDR-BT)...

Evaluation of a highly refined prediction model in knowledge-based volumetric modulated arc therapy planning for cervical cancer.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: To explore whether a highly refined dose volume histograms (DVH) prediction model can improve the accuracy and reliability of knowledge-based volumetric modulated arc therapy (VMAT) planning for cervical cancer.

Deep learning dose prediction for IMRT of esophageal cancer: The effect of data quality and quantity on model performance.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To investigate the effect of data quality and quantity on the performance of deep learning (DL) models, for dose prediction of intensity-modulated radiotherapy (IMRT) of esophageal cancer.

Clinical feasibility of deep learning-based auto-segmentation of target volumes and organs-at-risk in breast cancer patients after breast-conserving surgery.

Radiation oncology (London, England)
BACKGROUND: In breast cancer patients receiving radiotherapy (RT), accurate target delineation and reduction of radiation doses to the nearby normal organs is important. However, manual clinical target volume (CTV) and organs-at-risk (OARs) segmentat...

Self-channel-and-spatial-attention neural network for automated multi-organ segmentation on head and neck CT images.

Physics in medicine and biology
Accurate segmentation of organs at risk (OARs) is necessary for adaptive head and neck (H&N) cancer treatment planning, but manual delineation is tedious, slow, and inconsistent. A self-channel-and-spatial-attention neural network (SCSA-Net) is devel...

Comparison of the suitability of CBCT- and MR-based synthetic CTs for daily adaptive proton therapy in head and neck patients.

Physics in medicine and biology
Cone-beam computed tomography (CBCT)- and magnetic resonance (MR)-images allow a daily observation of patient anatomy but are not directly suited for accurate proton dose calculations. This can be overcome by creating synthetic CTs (sCT) using deep c...

Strategies to improve deep learning-based salivary gland segmentation.

Radiation oncology (London, England)
BACKGROUND: Deep learning-based delineation of organs-at-risk for radiotherapy purposes has been investigated to reduce the time-intensiveness and inter-/intra-observer variability associated with manual delineation. We systematically evaluated ways ...

Conquering Data Variations in Resolution: A Slice-Aware Multi-Branch Decoder Network.

IEEE transactions on medical imaging
Fully convolutional neural networks have made promising progress in joint liver and liver tumor segmentation. Instead of following the debates over 2D versus 3D networks (for example, pursuing the balance between large-scale 2D pretraining and 3D con...