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Organs at Risk

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Complete abdomen and pelvis segmentation using U-net variant architecture.

Medical physics
PURPOSE: Organ segmentation of computed tomography (CT) imaging is essential for radiotherapy treatment planning. Treatment planning requires segmentation not only of the affected tissue, but nearby healthy organs-at-risk, which is laborious and time...

Clinical evaluation of atlas- and deep learning-based automatic segmentation of multiple organs and clinical target volumes for breast cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Manual segmentation is the gold standard method for radiation therapy planning; however, it is time-consuming and prone to inter- and intra-observer variation, giving rise to interests in auto-segmentation methods. We evaluated the feasibility of dee...

Automatic IMRT planning via static field fluence prediction (AIP-SFFP): a deep learning algorithm for real-time prostate treatment planning.

Physics in medicine and biology
The purpose of this work was to develop a deep learning (DL) based algorithm, Automatic intensity-modulated radiotherapy (IMRT) Planning via Static Field Fluence Prediction (AIP-SFFP), for automated prostate IMRT planning with real-time planning effi...

Robustness study of noisy annotation in deep learning based medical image segmentation.

Physics in medicine and biology
Partly due to the use of exhaustive-annotated data, deep networks have achieved impressive performance on medical image segmentation. Medical imaging data paired with noisy annotation are, however, ubiquitous, but little is known about the effect of ...

A knowledge-based intensity-modulated radiation therapy treatment planning technique for locally advanced nasopharyngeal carcinoma radiotherapy.

Radiation oncology (London, England)
BACKGROUND: To investigate the feasibility of a knowledge-based automated intensity-modulated radiation therapy (IMRT) planning technique for locally advanced nasopharyngeal carcinoma (NPC) radiotherapy.

Using deep learning to predict beam-tunable Pareto optimal dose distribution for intensity-modulated radiation therapy.

Medical physics
PURPOSE: Many researchers have developed deep learning models for predicting clinical dose distributions and Pareto optimal dose distributions. Models for predicting Pareto optimal dose distributions have generated optimal plans in real time using an...

Auto-segmentation of organs at risk for head and neck radiotherapy planning: From atlas-based to deep learning methods.

Medical physics
Radiotherapy (RT) is one of the basic treatment modalities for cancer of the head and neck (H&N), which requires a precise spatial description of the target volumes and organs at risk (OARs) to deliver a highly conformal radiation dose to the tumor c...

Clinical Evaluation of Deep Learning and Atlas-Based Auto-Contouring of Bladder and Rectum for Prostate Radiation Therapy.

Practical radiation oncology
PURPOSE: Auto-contouring may reduce workload, interobserver variation, and time associated with manual contouring of organs at risk. Manual contouring remains the standard due in part to uncertainty around the time and workload savings after accounti...

Automatic segmentation of pelvic organs-at-risk using a fusion network model based on limited training samples.

Acta oncologica (Stockholm, Sweden)
Efficient and accurate methods are needed to automatically segmenting organs-at-risk (OAR) to accelerate the radiotherapy workflow and decrease the treatment wait time. We developed and evaluated the use of a fused model Dense V-Network for its abil...

RapidBrachyDL: Rapid Radiation Dose Calculations in Brachytherapy Via Deep Learning.

International journal of radiation oncology, biology, physics
PURPOSE: Detailed and accurate absorbed dose calculations from radiation interactions with the human body can be obtained with the Monte Carlo (MC) method. However, the MC method can be slow for use in the time-sensitive clinical workflow. The aim of...