BACKGROUND AND OBJECTIVE: The increasing dimensionality of healthcare datasets presents major challenges for clinical data analysis and interpretation. This study introduces a scalable ensemble feature selection (FS) strategy optimized for multi-biom...
INTRODUCTION: Knee osteoarthritis (KOA) is a prevalent cause of disability, marked by functional impairments that significantly reduce quality of life. Emerging digital health tools-particularly artificial intelligence (AI) and motion tracking techno...
The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst also being re...
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Sep 1, 2025
PURPOSE: Unlike established knee phenotype classifications, the recently introduced Citak classifications describe the intrafemoral and intratibial knee morphology. The aim of this study was to evaluate the distribution of Citak types A, B and C of t...
PURPOSE: In knee osteoarthritis (KOA) treatment, preventive measures to reduce its onset risk are a key factor. Among individuals with radiographically healthy knees, however, future knee joint integrity and condition cannot be predicted by clinicall...
BACKGROUND: Obtaining total knee arthroplasty patient-reported outcomes for quality assessment is costly and difficult. We asked whether a large language model (LLM) could interpret electronic health record notes to differentiate patients attaining a...
Osteoarthritis is a multifactorial condition marked by the gradual deterioration of joint cartilage, synovial inflammation, alterations in the subchondral bone and changes in the surrounding soft tissues. Clinical assessments and patient-reported out...
OBJECTIVE: In preclinical models of osteoarthritis (OA), histology is commonly used to evaluate joint remodeling. The current study introduces a deep learning driven histological analysis pipeline for the spatial evaluation of knee osteoarthritis (SE...
International journal of molecular sciences
May 15, 2025
Osteoarthritis (OA) is a prevalent and disabling chronic disease, with knee OA being the most common form, affecting approximately 73% of individuals over 55 years. Traditional clinical assessments often fail to predict knee structural progression ac...
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