AIMC Topic: Paper

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AI-Assisted Label-Free Monitoring Bone Mineral Metabolism on Demineralized Bone Paper.

ACS biomaterials science & engineering
Effective drug development for bone-related diseases, such as osteoporosis and metastasis, is hindered by the lack of physiologically relevant in vitro models. Traditional platforms, including standard tissue culture plastic, fail to replicate the st...

TimePAD─Unveiling Temporal Sequence ELISA Signal by Deep Learning for Rapid Readout and Improved Accuracy in a Microfluidic Paper-Based Analytical Platform.

Analytical chemistry
The integration of paper-based microfluidics with deep learning represents a pivotal trend in enhancing diagnostic capabilities. This paper introduces a new approach to improve the performance of a paper-based microfluidic enzyme-linked immunosorbent...

An artificial intelligence handheld sensor for direct reading of nickel ion and ethylenediaminetetraacetic acid in food samples using ratiometric fluorescence cellulose paper microfluidic chip.

International journal of biological macromolecules
User-friendly in-field sensing protocol is crucial for the effective tracing of intended analytes under less-developed countries or resources-limited environments. Nevertheless, existing sensing strategies require professional technicians and expensi...

Deep Learning-Based Kinetic Analysis in Paper-Based Analytical Cartridges Integrated with Field-Effect Transistors.

ACS nano
This study explores the fusion of a field-effect transistor (FET), a paper-based analytical cartridge, and the computational power of deep learning (DL) for quantitative biosensing via kinetic analyses. The FET sensors address the low sensitivity cha...

A Paper-Based Multiplexed Serological Test to Monitor Immunity against SARS-COV-2 Using Machine Learning.

ACS nano
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high infectivity and evolution of SARS-CoV-2, there is an ongoing interest...

Paper spray mass spectrometry combined with machine learning as a rapid diagnostic for chronic kidney disease.

The Analyst
A new analytical method for chronic kidney disease (CKD) detection utilizing paper spray mass spectrometry (PS-MS) combined with machine learning is presented. The analytical protocol is rapid and simple, based on metabolic profile alterations in uri...

Paper-based fluorescence sensor array with functionalized carbon quantum dots for bacterial discrimination using a machine learning algorithm.

Analytical and bioanalytical chemistry
The rapid discrimination of bacteria is currently an emerging trend in the fields of food safety, medical detection, and environmental observation. Traditional methods often require lengthy culturing processes, specialized analytical equipment, and b...

Combination of headspace single-drop microextraction (HS-SDME) with a nickel-embedded paper-based analytical device for cyanide quantification.

Analytica chimica acta
BACKGROUND: Cyanide anion can be found in foodstuffs, tobacco smoke and a variety of types of waters, mainly originating from anthropogenic activities. Due to its highly toxic nature, several agencies have established limits for cyanide levels in wat...

Deep learning-assisted ultra-accurate smartphone testing of paper-based colorimetric ELISA assays.

Analytica chimica acta
Smartphone has long been considered as one excellent platform for disease screening and diagnosis, especially when combined with microfluidic paper-based analytical devices (μPADs) that feature low cost, ease of use, and pump-free operations. In this...

Development of a paper-based analytical device for the colourimetric detection of alanine transaminase and the application of deep learning for image analysis.

Analytica chimica acta
A paper-based colourimetric assay for the detection of alanine transaminase has been developed. In the presence of alanine transaminase, 2,4-dinitrophenyl hydrazine changes to pyruvate hydrazone leading to a colour change from pale yellow to dark yel...