Patients with advanced Parkinson's disease regularly experience unstable motor states. Objective and reliable monitoring of these fluctuations is an unmet need. We used deep learning to classify motion data from a single wrist-worn IMU sensor recordi...
BACKGROUND: Up to 90% of patients with Parkinson's disease (PD) eventually develop the speech and voice disorder referred to as hypokinetic dysarthria (HD). However, the brain morphological changes associated with HD have not been investigated. Moreo...
Biomedical physics & engineering express
Mar 4, 2020
OBJECTIVES: Remote assessment of gait in patients' homes has become a valuable tool for monitoring the progression of Parkinson's disease (PD). However, these measurements are often not as accurate or reliable as clinical evaluations because it is ch...
International journal of medical informatics
Mar 3, 2020
OBJECTIVE: Predicting the risk of falls in advance can benefit the quality of care and potentially reduce mortality and morbidity in the older population. The aim of this study was to construct and validate an electronic health record-based fall risk...
In the last few years, the importance of measuring gait characteristics has increased tenfold due to their direct relationship with various neurological diseases. As patients suffering from Parkinson's disease (PD) are more prone to a movement disord...
BACKGROUND: Progressive supranuclear palsy (PSP), a neurodegenerative conditions may be difficult to discriminate clinically from idiopathic Parkinson's disease (PD). It is critical that we are able to do this accurately and as early as possible in o...
BACKGROUND: Recognition of human behavioral activities using local field potential (LFP) signals recorded from the Subthalamic Nuclei (STN) has applications in developing the next generation of deep brain stimulation (DBS) systems. DBS therapy is oft...
PURPOSE: Visibility of nigrosome 1 in the substantia nigra (SN) is used as an MR imaging biomarker for Parkinson's disease. Because of lower susceptibility induced tissue contrast and SNR visualization of the SN pars compacta (SNPC) using conventiona...
OBJECTIVE: To assess the classification performance between Parkinson's disease (PD) and normal control (NC) when semi-quantitative indicators and shape features obtained on dopamine transporter (DAT) single photon emission computed tomography (SPECT...
Tracking symptoms progression in the early stages of Parkinson's disease (PD) is a laborious endeavor as the disease can be expressed with vastly different phenotypes, forcing clinicians to follow a multi-parametric approach in patient evaluation, lo...
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