Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jul 4, 2023
BACKGROUND AND PURPOSE: Immunotherapy is a standard treatment for many tumor types. However, only a small proportion of patients derive clinical benefit and reliable predictive biomarkers of immunotherapy response are lacking. Although deep learning ...
Trends in plant science
Jun 30, 2023
Artificial intelligence (AI) is advancing rapidly and continually evolving in various fields. Recently, the release of ChatGPT has sparked significant public interest. In this study, we revisit the '100 Important Questions Facing Plant Science' by le...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 5, 2023
Genomic selection (GS) is expected to accelerate plant and animal breeding. During the last decade, genome-wide polymorphism data have increased, which has raised concerns about storage cost and computational time. Several individual studies have att...
Mammalian genome : official journal of the International Mammalian Genome Society
May 23, 2023
Echocardiography, a rapid and cost-effective imaging technique, assesses cardiac function and structure. Despite its popularity in cardiovascular medicine and clinical research, image-derived phenotypic measurements are manually performed, requiring ...
Artificial intelligence in medicine
May 20, 2023
Nowadays, it is really important and crucial to follow the new biomedical knowledge that is presented in scientific literature. To this end, Information Extraction pipelines can help to automatically extract meaningful relations from textual data tha...
Journal of molecular and cellular cardiology
May 13, 2023
Congenital long QT syndrome (LQTS) is characterized by a prolonged QT-interval on an electrocardiogram (ECG). An abnormal prolongation in the QT-interval increases the risk for fatal arrhythmias. Genetic variants in several different cardiac ion chan...
Analytical chemistry
May 10, 2023
Identification of a drug mechanism is vital for drug development. However, it often resorts to the expensive and cumbersome omics methods along with complex data analysis. Herein, we developed a methodology to analyze organelle staining images of sin...
Nature methods
May 8, 2023
Evolutionarily conserved signaling pathways are essential for early embryogenesis, and reducing or abolishing their activity leads to characteristic developmental defects. Classification of phenotypic defects can identify the underlying signaling mec...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Apr 29, 2023
Patient representation learning methods create rich representations of complex data and have potential to further advance the development of computational phenotypes (CP). Currently, these methods are either applied to small predefined concept sets o...
Science (New York, N.Y.)
Apr 28, 2023
Protein-coding differences between species often fail to explain phenotypic diversity, suggesting the involvement of genomic elements that regulate gene expression such as enhancers. Identifying associations between enhancers and phenotypes is challe...