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Pre-Eclampsia

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Development and validation of preeclampsia predictive models using key genes from bioinformatics and machine learning approaches.

Frontiers in immunology
BACKGROUND: Preeclampsia (PE) poses significant diagnostic and therapeutic challenges. This study aims to identify novel genes for potential diagnostic and therapeutic targets, illuminating the immune mechanisms involved.

Pseudo-random Number Generator Influences on Average Treatment Effect Estimates Obtained with Machine Learning.

Epidemiology (Cambridge, Mass.)
BACKGROUND: The use of machine learning to estimate exposure effects introduces a dependence between the results of an empirical study and the value of the seed used to fix the pseudo-random number generator.

Enhancing decision-making with linear diophantine multi-fuzzy set: application of novel information measures in medical and engineering fields.

Scientific reports
This study offers a comprehensive analysis of novel information for linear diophantine multi-fuzzy sets and illustrates its applications in practical scenarios. We introduce innovative similarity metrics tailored for linear diophantine multi-fuzzy se...

A comprehensive and bias-free machine learning approach for risk prediction of preeclampsia with severe features in a nulliparous study cohort.

BMC pregnancy and childbirth
Preeclampsia is one of the leading causes of maternal morbidity, with consequences during and after pregnancy. Because of its diverse clinical presentation, preeclampsia is an adverse pregnancy outcome that is uniquely challenging to predict and mana...

Identification of hub genes, diagnostic model, and immune infiltration in preeclampsia by integrated bioinformatics analysis and machine learning.

BMC pregnancy and childbirth
PURPOSE: This study aimed to identify novel biomarkers for preeclampsia (PE) diagnosis by integrating Weighted Gene Co-expression Network Analysis (WGCNA) with machine learning techniques.

NMF typing and machine learning algorithm-based exploration of preeclampsia-related mechanisms on ferroptosis signature genes.

Cell biology and toxicology
BACKGROUND: Globally, pre-eclampsia (PE) poses a major threat to the health and survival of pregnant women and fetuses, contributing significantly to morbidity and mortality. Recent studies suggest a pathological link between PE and ferroptosis. We a...

Prediction of pre-eclampsia with machine learning approaches: Leveraging important information from routinely collected data.

International journal of medical informatics
BACKGROUND: Globally, pre-eclampsia (PE) is a leading cause of maternal and perinatal morbidity and mortality. PE prediction using routinely collected data has the advantage of being widely applicable, particularly in low-resource settings. Early int...

Development of immune-derived molecular markers for preeclampsia based on multiple machine learning algorithms.

Scientific reports
Preeclampsia (PE) is a major pregnancy-specific cardiovascular complication posing latent life-threatening risks to mothers and neonates. The contribution of immune dysregulation to PE is not fully understood, highlighting the need to explore molecul...

Artificial Intelligence and Machine Learning in Preeclampsia.

Arteriosclerosis, thrombosis, and vascular biology
Preeclampsia is a multisystem hypertensive disorder that manifests itself after 20 weeks of pregnancy, along with proteinuria. The pathophysiology of preeclampsia is incompletely understood. Artificial intelligence, especially machine learning with i...