In the next 25 years, we will see unprecedented technological progress due to the artificial intelligence (AI) revolution. AI-driven advances will be made in five strongly interconnected domains: reenergised drug discovery, continuous real-time monit...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Nov 1, 2025
Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its poor prognosis and late diagnosis. Biomarkers are essential in enhancing diagnostic accuracy, prognostic assessments, and therapeutic strategies, thereby address...
UNLABELLED: The standard approach of using one-size-fits-all endocrine therapy for hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancers has faced significant challenges because of variations in tr...
UNLABELLED: Alterations to N6-methyladenosine (m6A) modifications can promote malignant progression by modulating gene expression through regulation of transcript metabolism. Quantifying the causal impact of m6A dysregulation at the population level ...
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, becoming a standard approach for various tumor types. Consequently, accurately predicting their efficacy has become crucial in clinical practice. Artificial intelligence (AI) h...
Neoantigens exhibit high immunogenic potential and confer a uniqueness to tumor cells, making them ideal targets for personalized cancer immunotherapy. Neoantigens originate from tumor-specific genetic alterations, abnormal viral infections, or other...
Studies in health technology and informatics
Sep 3, 2025
INTRODUCTION: Whole Exome Sequencing (WES) promises to open a new range of personalized treatments due to breaking the limits of former panel-based methods of molecular analysis. While the methodology is well established and already included in clini...
In critical care medicine, sepsis management represents a critical barrier to improving clinical outcomes, primarily due to the disease's profound heterogeneity and the current inability to optimally identify patient subgroups benefiting from persona...
BACKGROUND: Skin quality has a significant influence on aesthetic perception, yet its clinical evaluation remains subjective and inconsistent. Traditional assessments, such as visual grading and manual scoring, lack reproducibility and fail to captur...
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