Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), increase type 2 diabetes ris...
A fully automated and accurate assay of rare cell phenotypes in densely-packed fluorescently-labeled liquid biopsy images remains elusive. Employing a hybrid artificial intelligence (AI) paradigm that combines traditional rule-based morphological ma...
Journal of chemical information and modeling
Sep 1, 2020
Molecular dynamics (MD) simulations have been widely applied to study macromolecules including proteins. However, the high dimensionality of the data sets produced by simulations makes thorough analysis difficult and further hinders a deeper understa...
The characterization of the microbial population of many niches of the organism, as the gastrointestinal tract, is now possible thanks to the use of high-throughput DNA sequencing technique. Several studies in the companion animals field already inve...
Computational intelligence and neuroscience
Aug 10, 2020
An image target recognition approach based on mixed features and adaptive weighted joint sparse representation is proposed in this paper. This method is robust to the illumination variation, deformation, and rotation of the target image. It is a data...
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Aug 9, 2020
Late diagnosis of pancreatic cancer (PC) due to the limited effectiveness of modern testing approaches, causes many patients to miss the chance of surgery and consequently leads to a high mortality rate. Pivotal improvements in circulating microRNA e...
Analytical and bioanalytical chemistry
Aug 4, 2020
For the first time, a prototype HS-GC-MS-IMS dual-detection system is presented for the analysis of volatile organic compounds (VOCs) in fields of quality control of brewing hop. With a soft ionization and drift time-based ion separation in IMS and a...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jul 31, 2020
Pathogenic bio-aerosols are a threat to public health today, and thus quick detection and identification is of paramount importance. In this study, Raman spectroscopy was used to test 14 types of pollens, one type of fungus and two types of bacteria ...
Allele specific antibody response against the polymorphic system of HLA is the allogeneic response marker determining the immunological risk for graft acceptance before and after organ transplantation and therefore routinely studied during the patien...
The Alzheimer's Disease Neuroimaging (ADNI) database is an expansive undertaking by government, academia, and industry to pool resources and data on subjects at various stage of symptomatic severity due to Alzheimer's disease. As expected, magnetic r...