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Machine Learning Approaches for the Fusion of Near-Infrared, Mid-Infrared, and Raman Data to Identify Cartilage Degradation in Human Osteochondral Plugs.

Applied spectroscopy
Vibrational spectroscopy methods such as mid-infrared (MIR), near-infrared (NIR), and Raman spectroscopies have been shown to have great potential for in vivo biomedical applications, such as arthroscopic evaluation of joint injuries and degeneration...

Few-shot learning for inference in medical imaging with subspace feature representations.

PloS one
Unlike in the field of visual scene recognition, where tremendous advances have taken place due to the availability of very large datasets to train deep neural networks, inference from medical images is often hampered by the fact that only small amou...

Machine learning assisted dual-modal SERS detection for circulating tumor cells.

Biosensors & bioelectronics
Detecting circulating tumor cells (CTCs) from blood has become a promising approach for cancer diagnosis. Surface-enhanced Raman Spectroscopy (SERS) has rapidly developed as a significant detection technology for CTCs, offering high sensitivity and s...

A new approach to assess post-mortem interval: A machine learning-assisted label-free ATR-FTIR analysis of human vitreous humor.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
A crucial issue in forensics is determining the post-mortem interval (PMI), the time between death and the finding of a body. Despite various methods already employed for its estimation, only approximate values are currently achievable. Vitreous humo...

Enhancing endometrial cancer detection: Blood serum intrinsic fluorescence data processing and machine learning application.

Talanta
Endometrial cancer (EC) is the most prevalent cancer within the female reproductive system in developed countries. Despite its high incidence, there is currently no established laboratory screening test for EC, making early detection challenging. Thi...

Chemical composition alterations in rat brain hypothalamus induced by irisin administration using spectroscopic and machine learning techniques.

Analytical biochemistry
This study employed Fourier transform infrared (FTIR) spectroscopy to determine the chemical composition of brain tissues and the changes induced by irisin at doses of 50 mg and 100 mg. Brain tissues were collected from control rats and those adminis...

Development and evaluation of statistical and artificial intelligence approaches with microbial shotgun metagenomics data as an untargeted screening tool for use in food production.

mSystems
UNLABELLED: The increasing knowledge of microbial ecology in food products relating to quality and safety and the established usefulness of machine learning algorithms for anomaly detection in multiple scenarios suggests that the application of micro...

Self-Supervised Learning for Feature Extraction from Glomerular Images and Disease Classification with Minimal Annotations.

Journal of the American Society of Nephrology : JASN
BACKGROUND: Deep learning has great potential in digital kidney pathology. However, its effectiveness depends heavily on the availability of extensively labeled datasets, which are often limited because of the specialized knowledge and time required ...

Rapid diagnosis and recurrence prediction of choledocholithiasis disease using raw bile with machine learning assisted SERS.

Talanta
Surface-enhanced Raman spectroscopy (SERS) analysis based on body fluids has been widely applied in disease diagnose. Choledocholithiasis is a widespread and often recurrent digestive system disease, with limited data on factors predicting its format...

Spatially Resolved Fibre-Optic Probe for Cervical Precancer Detection Using Fluorescence Spectroscopy and PCA-ANN-Based Classification Algorithm: An In Vitro Study.

Journal of biophotonics
Cervical cancer can be detected at an early stage through the changes occurring in biochemical and morphological properties of epithelium layer. Fluorescence spectroscopy has the ability to identify these subtle changes non-invasively and in real tim...