AIMC Topic: Prognosis

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Machine learning model and hemoglobin to red cell distribution width ratio evaluates all-cause mortality in pulmonary embolism.

Scientific reports
The ratio of hemoglobin (Hb) to red blood cell distribution width (RDW), known as HRR, functions as an innovative indicator related to prognosis. However, whether HRR can predict the mortality for pulmonary embolism (PE) patients remains ambiguous. A...

Comparative study of five-year cervical cancer cause-specific survival prediction models based on SEER data.

Scientific reports
Cervical cancer (CC) is a major cause of mortality in women, with stagnant survival rates, highlighting the need for improved prognostic models. This study aims to develop and compare machine learning models for predicting five-year cause-specific su...

Development and validation of a transformer model-based early warning score for real-time prediction of adverse outcomes in the emergency department.

Scientific reports
This study aimed to develop and validate a transformer-based early warning score (TEWS) system for predicting adverse events (AEs) in the emergency department (ED). We conducted a retrospective study analyzing adult ED visits at a tertiary hospital. ...

Regulatory T cells and matrix-producing cancer associated fibroblasts contribute on the immune resistance and progression of prognosis related tumor subtypes in ccRCC.

Scientific reports
Clear cell renal cell carcinoma (ccRCC) is a prevalent malignant tumor in the field of urology. The effect of cell heterogeneity on the prognosis and reaction to treatment of ccRCC in large populations is still unclear. By analyzing public single cel...

Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma.

Scientific reports
Cancer-associated fibroblasts promote tumor progression through growth facilitation, invasion, and immune evasion. This study investigated the impact of activated cancer-associated fibroblasts (aCAFs) on survival outcomes, immune response, and molecu...

Comparison of AI chatbot predicted and realworld survival outcomes in hepatocellular carcinoma.

Scientific reports
This study compares survival predictions made by an artificial intelligence (AI) based chatbot with real-world data in hepatocellular carcinoma (HCC) patients. It aims to evaluate the reliability and accuracy of AI technologies in HCC prognosis. A re...

Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.

Scientific reports
Clear cell renal cell carcinoma (ccRCC) represents a prevalent malignant kidney tumor characterized by high metastatic potential and recurrence rates. Investigations into the molecular mechanisms and therapeutic targets of ccRCC have provided novel d...

Integrated analysis of shared gene expression signatures and immune microenvironment heterogeneity in type 2 diabetes mellitus and colorectal cancer.

Scientific reports
Emerging evidence suggests a bidirectional relationship between colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM), yet the shared molecular mechanisms and prognostic biomarkers remain poorly characterized. This study aimed to identify novel...

Machine learning developed LKB1-AMPK signaling related signature for prognosis and drug sensitivity in hepatocellular carcinoma.

Scientific reports
Hepatocellular carcinoma (HCC) is one of the most common tumors worldwide, posing a significant threat to the life and health of people globally. LKB1-AMPK signaling pathway plays a significant role in the regulation of cellular metabolism, prolifera...

Survival analysis for sepsis patients: A machine learning approach to feature selection and predictive modeling.

Scientific reports
Sepsis is a life-threatening condition that presents substantial challenges to healthcare and pharmacological management due to its high mortality rates and complex patient responses. Accurately predicting patient outcomes is essential for optimizing...