AIMC Topic: Prognosis

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Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.

International journal of radiation oncology, biology, physics
PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some p...

Improved prediction and risk stratification of major adverse cardiovascular events using an explainable machine learning approach combining plasma biomarkers and traditional risk factors.

Cardiovascular diabetology
BACKGROUND: Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality globally. Traditional risk models, primarily based on established risk factors, often lack the precision needed to accurately predict new-onset major advers...

An ensemble learning model to predict lymph node metastasis in early gastric cancer.

Scientific reports
Lymph node metastasis is a critical factor for determining therapeutic strategies and assessing the prognosis of early gastric cancer. This work aimed to establish a more dependable predictive model for identify lymph node metastasis in early gastric...

Identification of novel IL17-related genes as prognostic and therapeutic biomarkers of psoriasis using comprehensive bioinformatics analysis and machine learning.

Scientific reports
Psoriasis is a common chronic skin disorder with a polygenic background. It is widely acknowledged that Th17/IL-17A axis plays a key role in the pathogenesis of psoriasis. However, numerous regulatory genes upstream of the pathway remain undiscovered...

Data-Driven Prognostication in Distal Medium Vessel Occlusions Using Explainable Machine Learning.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Distal medium vessel occlusions (DMVOs) are estimated to cause acute ischemic stroke in 25%-40% of cases. Prognostic models can inform patient counseling and research by enabling outcome predictions. However, models designed s...

Advanced imaging techniques and artificial intelligence in pleural diseases: a narrative review.

European respiratory review : an official journal of the European Respiratory Society
BACKGROUND: Pleural diseases represent a significant healthcare burden, affecting over 350 000 patients annually in the US alone and requiring accurate diagnostic approaches for optimal management. Traditional imaging techniques have limitations in d...

Metabolomic machine learning-based model predicts efficacy of chemoimmunotherapy for advanced lung squamous cell carcinoma.

Frontiers in immunology
BACKGROUND: Unlike lung adenocarcinoma, patients with advanced squamous carcinoma exhibit a low proportion of driver gene positivity, with fewer effective treatment strategies available. Chemoimmunotherapy has now become the standard first-line treat...

Enlightened prognosis: Hepatitis prediction with an explainable machine learning approach.

PloS one
Hepatitis is a widespread inflammatory condition of the liver, presenting a formidable global health challenge. Accurate and timely detection of hepatitis is crucial for effective patient management, yet existing methods exhibit limitations that unde...

Development and validation of machine learning models for early diagnosis and prognosis of lung adenocarcinoma using miRNA expression profiles.

Cancer biomarkers : section A of Disease markers
ObjectiveStudy aims to develop diagnostic and prognostic models for lung adenocarcinoma (LUAD) using Machine learning(ML)algorithms, aiming to enhance clinical decision-making accuracy.MethodsData from The Cancer Genome Atlas (TCGA) for LUAD patients...

Foundation Model for Predicting Prognosis and Adjuvant Therapy Benefit From Digital Pathology in GI Cancers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Artificial intelligence (AI) holds significant promise for improving cancer diagnosis and treatment. Here, we present a foundation AI model for prognosis prediction on the basis of standard hematoxylin and eosin-stained histopathology slides...