AIMC Topic: Proportional Hazards Models

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sparsesurv: a Python package for fitting sparse survival models via knowledge distillation.

Bioinformatics (Oxford, England)
MOTIVATION: Sparse survival models are statistical models that select a subset of predictor variables while modeling the time until an event occurs, which can subsequently help interpretability and transportability. The subset of important features i...

Leveraging SEER data through machine learning to predict distant lymph node metastasis and prognosticate outcomes in hepatocellular carcinoma patients.

The journal of gene medicine
OBJECTIVES: This study aims to develop and validate machine learning-based diagnostic and prognostic models to predict the risk of distant lymph node metastases (DLNM) in patients with hepatocellular carcinoma (HCC) and to evaluate the prognosis for ...

CoxFNN: Interpretable machine learning method for survival analysis.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Survival analysis plays a pivotal role in healthcare, particularly in analyzing time-to-event data such as in disease progression, treatment efficacy, and drug development. Traditional methods in survival analysis often face a trade-off: they either ...

Personalized prediction of survival rate with combination of penalized Cox models in patients with colorectal cancer.

Medicine
The investigation into individual survival rates within the patient population was typically conducted using the Cox proportional hazards model. This study was aimed to evaluate the performance of machine learning algorithm in predicting survival rat...

Explainable machine learning predicts survival of retroperitoneal liposarcoma: A study based on the SEER database and external validation in China.

Cancer medicine
OBJECTIVE: We have developed explainable machine learning models to predict the overall survival (OS) of retroperitoneal liposarcoma (RLPS) patients. This approach aims to enhance the explainability and transparency of our modeling results.

Deep Learning-based Time-to-event Analysis of Depression and Asthma using the All of Us Research Program.

AMIA ... Annual Symposium proceedings. AMIA Symposium
While there is a growing recognition of the association between depression and asthma, few studies have leveraged deep learning-based (DL-based) models in a retrospective cohort study with a large sample size. We analyzed the association between depr...

Machine Learning-Based Pathomics Model to Predict the Prognosis in Clear Cell Renal Cell Carcinoma.

Technology in cancer research & treatment
Clear cell renal cell carcinoma (ccRCC) is a highly lethal urinary malignancy with poor overall survival (OS) rates. Integrating computer vision and machine learning in pathomics analysis offers potential for enhancing classification, prognosis, and ...

An online framework for survival analysis: reframing Cox proportional hazards model for large data sets and neural networks.

Biostatistics (Oxford, England)
In many biomedical applications, outcome is measured as a "time-to-event" (e.g., disease progression or death). To assess the connection between features of a patient and this outcome, it is common to assume a proportional hazards model and fit a pro...

[Cox model analysis of curative effect and prognostic factors of oral robot-assisted RPLN dissection for head and neck malignancies].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To investigate the efficacy and prognostic factors of oral robot-assisted retropharyngeal lymph node (RPLN) dissection in the treatment of head and neck malignancies.

Statistical and Machine Learning Methods for Discovering Prognostic Biomarkers for Survival Outcomes.

Methods in molecular biology (Clifton, N.J.)
Discovering molecular biomarkers for predicting patient survival outcomes is an essential step toward improving prognosis and therapeutic decision-making in the treatment of severe diseases such as cancer. Due to the high-dimensionality nature of omi...