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Radiopharmaceuticals

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Acquisition time reduction in pediatric Tc-DMSA planar imaging using deep learning.

Journal of applied clinical medical physics
PURPOSE: Given the potential risk of motion artifacts, acquisition time reduction is desirable in pediatric Tc-dimercaptosuccinic acid (DMSA) scintigraphy. The aim of this study was to evaluate the performance of predicted full-acquisition-time imag...

The emerging role of artificial intelligence and digital twins in pre-clinical molecular imaging.

Nuclear medicine and biology
INTRODUCTION: Pre-clinical molecular imaging, particularly with mice, is an essential part of drug and radiopharmaceutical development. There remain ethical challenges to reduce, refine and replace animal imaging where possible.

Artificial Contrast: Deep Learning for Reducing Gadolinium-Based Contrast Agents in Neuroradiology.

Investigative radiology
Deep learning approaches are playing an ever-increasing role throughout diagnostic medicine, especially in neuroradiology, to solve a wide range of problems such as segmentation, synthesis of missing sequences, and image quality improvement. Of parti...

Deep learning model integrating positron emission tomography and clinical data for prognosis prediction in non-small cell lung cancer patients.

BMC bioinformatics
BACKGROUND: Lung cancer is the leading cause of cancer-related deaths worldwide. The majority of lung cancers are non-small cell lung cancer (NSCLC), accounting for approximately 85% of all lung cancer types. The Cox proportional hazards model (CPH),...

Machine learning-based approach reveals essential features for simplified TSPO PET quantification in ischemic stroke patients.

Zeitschrift fur medizinische Physik
INTRODUCTION: Neuroinflammation evaluation after acute ischemic stroke is a promising option for selecting an appropriate post-stroke treatment strategy. To assess neuroinflammation in vivo, translocator protein PET (TSPO PET) can be used. However, t...

Bone tumor necrosis rate detection in few-shot X-rays based on deep learning.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Although biopsy-based necrosis rate is a golden standard for reflecting the sensitivity of bone tumor and guiding postoperative chemotherapy, it requires biopsy which is invasive and time-consuming. In this paper, we develop a new necrosis rate detec...

Breast PET/MRI Hybrid Imaging and Targeted Tracers.

Journal of magnetic resonance imaging : JMRI
The recent introduction of hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) as a promising imaging modality for breast cancer assessment has prompted fervent research activity on its clinical applications. The current knowledg...

Technical note: Rapid and high-resolution deep learning-based radiopharmaceutical imaging with 3D-CZT Compton camera and sparse projection data.

Medical physics
BACKGROUND: The Compton camera (CC) has great potential in nuclear medicine imaging due to the high detection efficiency and the ability to simultaneously detect multi-energy radioactive sources. However, the finite resolution of the detectors will d...

Quantitative evaluation of a deep learning-based framework to generate whole-body attenuation maps using LSO background radiation in long axial FOV PET scanners.

European journal of nuclear medicine and molecular imaging
PURPOSE: Attenuation correction is a critically important step in data correction in positron emission tomography (PET) image formation. The current standard method involves conversion of Hounsfield units from a computed tomography (CT) image to cons...

Deep learning based time-to-event analysis with PET, CT and joint PET/CT for head and neck cancer prognosis.

Computer methods and programs in biomedicine
OBJECTIVES: Recent studies have shown that deep learning based on pre-treatment positron emission tomography (PET) or computed tomography (CT) is promising for distant metastasis (DM) and overall survival (OS) prognosis in head and neck cancer (HNC)....