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Radiotherapy Planning, Computer-Assisted

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Radiotherapy dose prediction using off-the-shelf segmentation networks: A feasibility study with GammaPod planning.

Medical physics
BACKGROUND: Radiotherapy requires precise, patient-specific treatment planning to achieve high-quality dose distributions that improve patient outcomes. Traditional manual planning is time-consuming and clinically impractical for performing necessary...

Development and validation of a deep reinforcement learning algorithm for auto-delineation of organs at risk in cervical cancer radiotherapy.

Scientific reports
This study was conducted to develop and validate a novel deep reinforcement learning (DRL) algorithm incorporating the segment anything model (SAM) to enhance the accuracy of automatic contouring organs at risk during radiotherapy for cervical cancer...

Incorporating indirect MRI information in a CT-based deep learning model for prostate auto-segmentation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Computed tomography (CT) imaging poses challenges for delineation of soft tissue structures for prostate cancer external beam radiotherapy. Guidelines require the input of magnetic resonance imaging (MRI) information. We devel...

A knowledge-based planning model to identify fraction-reduction opportunities in brain stereotactic radiotherapy.

Journal of applied clinical medical physics
OBJECTIVE: To develop and validate a HyperArc-based RapidPlan (HARP) model for three-fraction brain stereotactic radiotherapy (SRT) plans to then use to replan previously treated five-fraction SRT plans. Demonstrating the possibility of reducing the ...

Dose prediction via deep learning to enhance treatment planning of lung radiotherapy including simultaneous integrated boost techniques.

Medical physics
BACKGROUND: Recent studies have shown deep learning techniques are able to predict three-dimensional (3D) dose distributions of radiotherapy treatment plans. However, their use in dose prediction for treatments with varied prescription doses includin...

Deep learning techniques for proton dose prediction across multiple anatomical sites and variable beam configurations.

Physics in medicine and biology
To evaluate the impact of beam mask implementation and data aggregation on artificial intelligence-based dose prediction accuracy in proton therapy, with a focus on scenarios involving limited or highly heterogeneous datasets.In this study, 541 prost...

Enhanced dose prediction for head and neck cancer artificial intelligence-driven radiotherapy based on transfer learning with limited training data.

Journal of applied clinical medical physics
PURPOSE: Training deep learning dose prediction models for the latest cutting-edge radiotherapy techniques, such as AI-based nodal radiotherapy (AINRT) and Daily Adaptive AI-based nodal radiotherapy (DA-AINRT), is challenging due to limited data. Thi...

Deep learning-based segmentation of head and neck organs at risk on CBCT images with dosimetric assessment for radiotherapy.

Physics in medicine and biology
Cone beam computed tomography (CBCT) has become an essential tool in head and neck cancer (HNC) radiotherapy (RT) treatment delivery. Automatic segmentation of the organs at risk (OARs) on CBCT can trigger and accelerate treatment replanning but is s...

Initial characterization of a novel dual-robot orthovoltage radiotherapy system.

Biomedical physics & engineering express
Adequate access to radiotherapy is a critical global concern affecting low-resource settings such as low- and middle-income countries and rural regions. We propose to reduce this disparity by developing a novel low-cost radiotherapy device that treat...

A deep learning model for inter-fraction head and neck anatomical changes in proton therapy.

Physics in medicine and biology
To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients.A probabilistic daily anatomy model (DAM) for head and neck patients DAM (DAM) is built on the varia...