AIMC Topic: Radiotherapy Planning, Computer-Assisted

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Auto-segmentation of important centers of growth in the pediatric skeleton to consider during radiation therapy based on deep learning.

Medical physics
BACKGROUND: Routinely delineating of important skeletal growth centers is imperative to mitigate radiation-induced growth abnormalities for pediatric cancer patients treated with radiotherapy. However, it is hindered by several practical problems, in...

A deep learning approach to generate synthetic CT in low field MR-guided radiotherapy for lung cases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
INTRODUCTION: This study aims to apply a conditional Generative Adversarial Network (cGAN) to generate synthetic Computed Tomography (sCT) from 0.35 Tesla Magnetic Resonance (MR) images of the thorax.

Artificial intelligence in radiotherapy.

Seminars in cancer biology
Radiotherapy is a discipline closely integrated with computer science. Artificial intelligence (AI) has developed rapidly over the past few years. With the explosive growth of medical big data, AI promises to revolutionize the field of radiotherapy t...

Development of deep learning chest X-ray model for cardiac dose prediction in left-sided breast cancer radiotherapy.

Scientific reports
Deep inspiration breath-hold (DIBH) is widely used to reduce the cardiac dose in left-sided breast cancer radiotherapy. This study aimed to develop a deep learning chest X-ray model for cardiac dose prediction to select patients with a potentially hi...

Evaluation of auto-segmentation for EBRT planning structures using deep learning-based workflow on cervical cancer.

Scientific reports
Deep learning (DL) based approach aims to construct a full workflow solution for cervical cancer with external beam radiation therapy (EBRT) and brachytherapy (BT). The purpose of this study was to evaluate the accuracy of EBRT planning structures de...

A novel multichannel deep learning model for fast denoising of Monte Carlo dose calculations: preclinical applications.

Physics in medicine and biology
In preclinical radiotherapy with kilovolt (kV) x-ray beams, accurate treatment planning is needed to improve the translation potential to clinical trials. Monte Carlo based radiation transport simulations are the gold standard to calculate the absorb...

A New Approach to Quantify and Grade Radiation Dermatitis Using Deep-Learning Segmentation in Skin Photographs.

Clinical oncology (Royal College of Radiologists (Great Britain))
AIMS: Objective evaluation of radiation dermatitis is important for analysing the correlation between the severity of radiation dermatitis and dose distribution in clinical practice and for reliable reporting in clinical trials. We developed a novel ...

Fast VMAT planning for prostate radiotherapy: dosimetric validation of a deep learning-based initial segment generation method.

Physics in medicine and biology
. To develop and evaluate a deep learning based fast volumetric modulated arc therapy (VMAT) plan generation method for prostate radiotherapy.. A customized 3D U-Net was trained and validated to predict initial segments at 90 evenly distributed contr...

Clinical Validation of a Deep-Learning Segmentation Software in Head and Neck: An Early Analysis in a Developing Radiation Oncology Center.

International journal of environmental research and public health
BACKGROUND: Organs at risk (OARs) delineation is a crucial step of radiotherapy (RT) treatment planning workflow. Time-consuming and inter-observer variability are main issues in manual OAR delineation, mainly in the head and neck (H & N) district. D...

A deep image-to-image network organ segmentation algorithm for radiation treatment planning: principles and evaluation.

Radiation oncology (London, England)
BACKGROUND: We describe and evaluate a deep network algorithm which automatically contours organs at risk in the thorax and pelvis on computed tomography (CT) images for radiation treatment planning.