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Rats

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Human and rat microsomal metabolites of N-tert-butoxycarbonylmethamphetamine and its urinary metabolites in rat.

Forensic toxicology
PURPOSE: N-tert-Butoxycarbonylmethamphetamine (BocMA), a masked derivative of methamphetamine (MA), converts into MA under acidic condition and potentially acts as a precursor to MA following ingestion. To investigate the metabolism and excretion of ...

Ferromagnetic soft catheter robots for minimally invasive bioprinting.

Nature communications
In vivo bioprinting has recently emerged as a direct fabrication technique to create artificial tissues and medical devices on target sites within the body, enabling advanced clinical strategies. However, existing in vivo bioprinting methods are ofte...

Linear and non-linear feature extraction from rat electrocorticograms for seizure detection by support vector machine.

Biomedizinische Technik. Biomedical engineering
Seizures, the main symptom of epilepsy, are provoked due to a neurological disorder that underlies the disease. The accurate detection of seizures is a crucial step in any procedure of treatment. In the present study, electrocorticogram (ECoG) signal...

AI Enabled IoRT Framework for Rodent Activity Monitoring in a False Ceiling Environment.

Sensors (Basel, Switzerland)
Routine rodent inspection is essential to curbing rat-borne diseases and infrastructure damages within the built environment. Rodents find false ceilings to be a perfect spot to seek shelter and construct their habitats. However, a manual false ceili...

LiftPose3D, a deep learning-based approach for transforming two-dimensional to three-dimensional poses in laboratory animals.

Nature methods
Markerless three-dimensional (3D) pose estimation has become an indispensable tool for kinematic studies of laboratory animals. Most current methods recover 3D poses by multi-view triangulation of deep network-based two-dimensional (2D) pose estimate...

Skilled reach training enhances robotic gait training to restore overground locomotion following spinal cord injury in rats.

Behavioural brain research
Rehabilitative training has been shown to improve motor function following spinal cord injury (SCI). Unfortunately, these gains are primarily task specific; where reach training only improves reaching, step training only improves stepping and stand t...

Interpreting wide-band neural activity using convolutional neural networks.

eLife
Rapid progress in technologies such as calcium imaging and electrophysiology has seen a dramatic increase in the size and extent of neural recordings. Even so, interpretation of this data requires considerable knowledge about the nature of the repres...

Guide-Wired Helical Microrobot for Percutaneous Revascularization in Chronic Total Occlusion in-Vivo Validation.

IEEE transactions on bio-medical engineering
OBJECTIVE: For the revascularization in small vessels such as coronary arteries, we present a guide-wired helical microrobot mimicking the corkscrew motion for mechanical atherectomy that enables autonomous therapeutics and minimizing the radiation e...

Epileptic Seizure Detection on an Ultra-Low-Power Embedded RISC-V Processor Using a Convolutional Neural Network.

Biosensors
The treatment of refractory epilepsy via closed-loop implantable devices that act on seizures either by drug release or electrostimulation is a highly attractive option. For such implantable medical devices, efficient and low energy consumption, smal...

Ischemic stroke-induced polyaxonal innervation at the neuromuscular junction is attenuated by robot-assisted mechanical therapy.

Experimental neurology
Ischemic stroke is a leading cause of disability world-wide. Mounting evidence supports neuromuscular pathology following stroke, yet mechanisms of dysfunction and therapeutic action remain undefined. The objectives of our study were to investigate n...