BACKGROUND: The TaqMan Array Card (TAC) is an arrayed, high-throughput qPCR platform that can simultaneously detect multiple targets in a single reaction. However, the manual post-run analysis of TAC data is time consuming and subject to interpretati...
OBJECTIVES: In Multiple Sclerosis (MS) cerebral MRI is essential for disease and treatment monitoring. For this purpose, software solutions are available to support the radiologist with image interpretation and reporting of follow up imaging. Aim of ...
Cardio Vascular Disease (CVD) is one of the leading causes of mortality and it is estimated that 1 in 4 deaths happens due to it. The disease prevalence rate becomes higher since there is an inadequate system/model for predicting CVD at an earliest. ...
BACKGROUND AND OBJECTIVE: Randomized controlled trials (RCTs) are the cornerstone of evidence-based medicine. Unfortunately, not all RCTs are based on real data. This serious breach of research integrity compromises the reliability of systematic revi...
This study aimed to analyze the impact of acidic conditions on the recovery of ciprofloxacin and levofloxacin for cloud point extraction with the Design of Experiments and Artificial Neural Networks. The design included 27 experiments featuring three...
BACKGROUND: Artificial intelligence (AI) and large language models (LLMs) like ChatGPT have transformed information retrieval, including in healthcare. ChatGPT, trained on diverse datasets, can provide medical advice but faces ethical and accuracy co...
International journal of pharmaceutics
Jan 16, 2025
In the field of pharmaceutical research, Lipinski's Rule of Five (RO5) was once widely regarded as the prevailing standard for the development of novel drugs. Despite the fact that an increasing number of recently approved drugs no longer adhere to t...
There is growing interest in using deep learning models to automate wildlife detection in aerial imaging surveys to increase efficiency, but human-generated annotations remain necessary for model training. However, even skilled observers may diverge ...
: Measuring joint range of motion (ROM) is essential for diagnosing and treating musculoskeletal diseases. However, most clinical measurements are conducted using conventional devices, and their reliability may significantly depend on the tester. Thi...
PURPOSE: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients with various glaucoma types and severities using clinical trial data. This study assesses performance ...