Journal of chemical information and modeling
Dec 20, 2019
The ultimate goal of drug design is to find novel compounds with desirable pharmacological properties. Designing molecules retaining particular scaffolds as their core structures is an efficient way to obtain potential drug candidates. We propose a s...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Dec 20, 2019
PURPOSE: In proton therapy, imaging prompt gamma (PG) rays has the potential to verify proton dose (PD) distribution. Despite the fact that there is a strong correlation between the gamma-ray emission and PD, they are still different in terms of the ...
Computational and mathematical methods in medicine
Dec 19, 2019
Machine learning, one of the core disciplines of artificial intelligence, is an approach whose main emphasis is analytical model building. In other words, machine learning enables an automaton to make its own decisions based on a previous training pr...
Absolute quantitation of IgG-1 Fc-glycosylation, which is crucial for the clinical practice of glyco-biomarkers and quality control of biopharmaceuticals, has been hindered by the lack of glycopeptide standards. In this study, eleven high abundant Ig...
An original dual signal amplification immunoassay for N-Terminal pro-brain natriuretic peptide (NT-proBNP) detection is developed based on Au NPs and Zn doped CdS nanoparticles (ZnCdS) co-sensitized BiMoO nanosheet photoelectrochemical (PEC) platform...
Mixtures analysis can provide more information than individual components. It is important to detect the different compounds in the real complex samples. However, mixtures are often disturbed by impurities and noise to influence the accuracy. Purific...
Uncertainty of labels in clinical data resulting from intra-observer variability can have direct impact on the reliability of assessments made by deep neural networks. In this paper, we propose a method for modelling such uncertainty in the context o...
BACKGROUND: Although analysis of cardiac magnetic resonance (CMR) images provides accurate and reproducible measurements of left ventricular (LV) volumes, these measurements are usually not performed throughout the cardiac cycle because of lack of to...
Computational and mathematical methods in medicine
Dec 12, 2019
Photoplethysmography (PPG) has been widely used in noninvasive blood volume and blood flow detection since its first appearance. However, its noninvasiveness also makes the PPG signals vulnerable to noise interference and thus exhibits nonlinear and ...
OBJECTIVES: To evaluate whether a computed tomography (CT) radiomics-based machine learning classifier can predict histopathology of lymph nodes (LNs) after post-chemotherapy LN dissection (pcRPLND) in patients with metastatic non-seminomatous testic...
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