AIMC Topic: Reproducibility of Results

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CD-Based Indices for Link Prediction in Complex Network.

PloS one
Lots of similarity-based algorithms have been designed to deal with the problem of link prediction in the past decade. In order to improve prediction accuracy, a novel cosine similarity index CD based on distance between nodes and cosine value betwee...

The Best Model of a Cat Is Several Cats.

Trends in biotechnology
Modern biotechnology is emerging at the intersection of engineering, biology, physics, and computer science. As such it carries with it history from several disparate fields of research including a strong tradition in deductive reasoning primarily de...

Identifying a clinical signature of suicidality among patients with mood disorders: A pilot study using a machine learning approach.

Journal of affective disorders
OBJECTIVE: A growing body of evidence has put forward clinical risk factors associated with patients with mood disorders that attempt suicide. However, what is not known is how to integrate clinical variables into a clinically useful tool in order to...

Simultaneous quantification of 5 main components of Psoralea corylifolia L. in rats' plasma by utilizing ultra high pressure liquid chromatography tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Psoralea corylifolia L. has long been used in traditional Chinese medicine for treating and preventing many diseases. A group of flavonoid components are regarded as the active principals within the seeds. In this research, a rapid, accurate and sens...

Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
An ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of (4S,5R)-5-[3,5-bis (trifluoromethyl)phenyl]-3-{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl] met...

Neural Networks Technique for Filling Gaps in Satellite Measurements: Application to Ocean Color Observations.

Computational intelligence and neuroscience
A neural network (NN) technique to fill gaps in satellite data is introduced, linking satellite-derived fields of interest with other satellites and in situ physical observations. Satellite-derived "ocean color" (OC) data are used in this study becau...

A Turn-On Resonance Raman Scattering (BCS/Cu+) Sensor for Quantitative Determination of Proteins.

Applied spectroscopy
In this study, a new method for the quantitative evaluation of proteins is developed using competitive resonance Raman spectroscopy. A chelation reaction between bathocuproine disulfonate (BCS) and Cu(+) which is reduced by proteins in an alkaline en...

Determination of residual dextran sulfate in protein products by SEC-HPLC.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dextran sulfate is a polyanionic derivative of dextran, produced by esterification of dextran with chlorosulphonic acid. Dextran sulfate with an average molecular weight of 8000Da can be added to the cell culture to inhibit binding of proteins to cel...

Quantitative analysis of maytansinoid (DM1) in human serum by on-line solid phase extraction coupled with liquid chromatography tandem mass spectrometry - Method validation and its application to clinical samples.

Journal of pharmaceutical and biomedical analysis
A sensitive and specific method was developed and validated for the quantitation of maytansinoid (DM1) in human serum using on-line solid phase extraction (SPE)-liquid chromatography-tandem mass spectrometry (LC-MS/MS). Because DM1 contains a free th...