AIMC Topic: Research Design

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Validation of a Cyclic Algorithm to Proxy Number of Lines of Systemic Cancer Therapy Using Administrative Data.

JCO clinical cancer informatics
PURPOSE: Researchers are automating the process for identifying the number of lines of systemic cancer therapy received by patients. To date, algorithm development has involved manual modifications to predefined classification rules. In this study, w...

A deep learning technique for imputing missing healthcare data.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Missing data is a frequent occurrence in medical and health datasets. The analysis of datasets with missing data can lead to loss in statistical power or biased results. We address this issue with a novel deep learning technique to impute missing val...

Citizen science frontiers: Efficiency, engagement, and serendipitous discovery with human-machine systems.

Proceedings of the National Academy of Sciences of the United States of America
Citizen science has proved to be a unique and effective tool in helping science and society cope with the ever-growing data rates and volumes that characterize the modern research landscape. It also serves a critical role in engaging the public with ...

Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Persistent spiking has been thought to underlie working memory (WM). However, virtually all of the evidence for this comes from studies that averaged spiking across time and across trials, which masks the details. On single trials, activity often occ...

The economic cost of robotic rehabilitation for adult stroke patients: a systematic review protocol.

JBI database of systematic reviews and implementation reports
The objective of this review is to identify the best available evidence on the economic cost of robotic rehabilitation for adult stroke patients to improve their motor movement abilities. More specifically, the objective is to identify the evidence o...

Cardiorenal Outcomes in the CANVAS, DECLARE-TIMI 58, and EMPA-REG OUTCOME Trials: A Systematic Review.

Reviews in cardiovascular medicine
In this systematic review, we sought to summarize the 3 recent sodium-glucose cotransporter 2 inhibitor (SGLT2i) trials (Dapagliflozin Effect on CardiovasculAR Events (DECLARE-TIMI 58), Canagliflozin Cardiovascular Assessment Study (CANVAS) Program, ...

Towards Phenotyping of Clinical Trial Eligibility Criteria.

Studies in health technology and informatics
BACKGROUND: Medical plaintext documents contain important facts about patients, but they are rarely available for structured queries. The provision of structured information from natural language texts in addition to the existing structured data can ...

Introduction to special section on advanced methodology: Counseling the dog to wag its methodological tail.

Journal of counseling psychology
In this article, we introduce a special section focused on the application of advanced methodologies to specific research questions in counseling psychology. The articles include applications of natural language processing, dynamic systems, mediation...