Understanding how risk factors interact to jointly influence disease risk can provide insights into disease development and improve risk prediction. Here we introduce survivalFM, a machine learning extension to the widely used Cox proportional hazard...
BACKGROUND: Machine learning (ML) models may offer greater clinical utility than conventional risk scores, such as the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores. However, there is a ...
OBJECTIVES: This study aims to explore the role of intra- and peri-tumoral radiomics features in tumor risk prediction, with a particular focus on the impact of peri-tumoral characteristics on the tumor microenvironment.
INTRODUCTION: Predictive scoring systems support clinicians in decision-making by estimating the prognosis of patients in intensive care units (ICUs). However, there is limited evidence on the accuracy of these systems in predicting mortality and org...
Journal of the American College of Surgeons
Jul 16, 2025
BACKGROUND: Financial toxicity (FT) refers to the financial stress and detrimental impact on quality of life experienced by patients due to treatment cost. In patients with resected lung cancer (LC), we sought to identify those at risk of developing ...
OBJECTIVES: To develop and validate a machine learning model for precise risk stratification of postpancreaticoduodenectomy haemorrhage (PPH), enabling early identification of high-risk patients to guide clinical intervention.
BACKGROUND: Sepsis-associated delirium (SAD) occurs due to disruptions in neurotransmission linked to inflammatory responses from infections. It poses significant challenges in clinical management and is associated with poor outcomes. Survivors often...
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Jul 15, 2025
BACKGROUND: Survival of patients with high-risk hepatoblastoma remains low, and early identification of high-risk hepatoblastoma is critical.
Synthetic chemicals are intensively utilized in modern societies, and their mixtures pose significant health and ecological threats. Nontarget screening (NTS) analysis allows for the simultaneous chemical identification and quantitative reporting of ...
BMC medical informatics and decision making
Jul 15, 2025
BACKGROUND: Drug-induced immune thrombocytopenia (DITP) is a rare but potentially life-threatening adverse drug reaction, often underrecognized due to its nonspecific presentation and the lack of real-time diagnostic tools. Early identification of at...
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