AIMC Topic: Risk Assessment

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Comprehensive interaction modeling with machine learning improves prediction of disease risk in the UK Biobank.

Nature communications
Understanding how risk factors interact to jointly influence disease risk can provide insights into disease development and improve risk prediction. Here we introduce survivalFM, a machine learning extension to the widely used Cox proportional hazard...

Comparing the Performance of Machine Learning Models and Conventional Risk Scores for Predicting Major Adverse Cardiovascular Cerebrovascular Events After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: Machine learning (ML) models may offer greater clinical utility than conventional risk scores, such as the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores. However, there is a ...

Integrative radiomics of intra- and peri-tumoral features for enhanced risk prediction in thymic tumors: a multimodal analysis of tumor microenvironment contributions.

BMC medical imaging
OBJECTIVES: This study aims to explore the role of intra- and peri-tumoral radiomics features in tumor risk prediction, with a particular focus on the impact of peri-tumoral characteristics on the tumor microenvironment.

Effectiveness of predictive scoring systems in predicting mortality in relation to baseline kidney function in adult intensive care unit patients: a systematic review protocol.

BMJ open
INTRODUCTION: Predictive scoring systems support clinicians in decision-making by estimating the prognosis of patients in intensive care units (ICUs). However, there is limited evidence on the accuracy of these systems in predicting mortality and org...

Machine Learning Prediction of Financial Toxicity in Patients with Resected Lung Cancer.

Journal of the American College of Surgeons
BACKGROUND: Financial toxicity (FT) refers to the financial stress and detrimental impact on quality of life experienced by patients due to treatment cost. In patients with resected lung cancer (LC), we sought to identify those at risk of developing ...

Machine learning model for postpancreaticoduodenectomy haemorrhage prediction: an international multicentre cohort study.

BMJ open
OBJECTIVES: To develop and validate a machine learning model for precise risk stratification of postpancreaticoduodenectomy haemorrhage (PPH), enabling early identification of high-risk patients to guide clinical intervention.

Development of a risk prediction model for sepsis-related delirium based on multiple machine learning approaches and an online calculator.

PloS one
BACKGROUND: Sepsis-associated delirium (SAD) occurs due to disruptions in neurotransmission linked to inflammatory responses from infections. It poses significant challenges in clinical management and is associated with poor outcomes. Survivors often...

Identification of high-risk hepatoblastoma in the CHIC risk stratification system based on enhanced CT radiomics features.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Survival of patients with high-risk hepatoblastoma remains low, and early identification of high-risk hepatoblastoma is critical.

Nontarget Screening Analysis Combined with Computational Toxicology: A Promising Solution for Identification and Risk Assessment of Environmental Pollutants in the Big Data Era.

Environmental science & technology
Synthetic chemicals are intensively utilized in modern societies, and their mixtures pose significant health and ecological threats. Nontarget screening (NTS) analysis allows for the simultaneous chemical identification and quantitative reporting of ...

Development and external validation of a machine learning model for predicting drug-induced immune thrombocytopenia in a real-world hospital cohort.

BMC medical informatics and decision making
BACKGROUND: Drug-induced immune thrombocytopenia (DITP) is a rare but potentially life-threatening adverse drug reaction, often underrecognized due to its nonspecific presentation and the lack of real-time diagnostic tools. Early identification of at...