AIMC Topic: ROC Curve

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Higher Serum Endocan Level Is Associated with Alzheimer Disease.

Dementia and geriatric cognitive disorders
BACKGROUND: The novel molecule endocan, which is released by endothelium and is regulated by proangiogenic and proinflammatory cytokines, may have a role in the pathophysiology of Alzheimer disease (AD). The aim of this study was to evaluate the rela...

Classification of Pre-Clinical Seizure States Using Scalp EEG Cross-Frequency Coupling Features.

IEEE transactions on bio-medical engineering
OBJECTIVE: This work proposes a machine-learning based system for a scalp EEG that flags an alarm in advance of a clinical seizure onset.

Semi-Supervised Discriminative Classification Robust to Sample-Outliers and Feature-Noises.

IEEE transactions on pattern analysis and machine intelligence
Discriminative methods commonly produce models with relatively good generalization abilities. However, this advantage is challenged in real-world applications (e.g., medical image analysis problems), in which there often exist outlier data points (sa...

A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Cell cycle (Georgetown, Tex.)
Personalized medicine implies that distinct treatment methods are prescribed to individual patients according several features that may be obtained from, e.g., gene expression profile. The majority of machine learning methods suffer from the deficien...

Federated learning of predictive models from federated Electronic Health Records.

International journal of medical informatics
BACKGROUND: In an era of "big data," computationally efficient and privacy-aware solutions for large-scale machine learning problems become crucial, especially in the healthcare domain, where large amounts of data are stored in different locations an...

Revealing Alzheimer's disease genes spectrum in the whole-genome by machine learning.

BMC neurology
BACKGROUND: Alzheimer's disease (AD) is an important, progressive neurodegenerative disease, with a complex genetic architecture. A key goal of biomedical research is to seek out disease risk genes, and to elucidate the function of these risk genes i...

An ensemble boosting model for predicting transfer to the pediatric intensive care unit.

International journal of medical informatics
BACKGROUND: Early deterioration indicators have the potential to alert hospital care staff in advance of adverse events, such as patients requiring an increased level of care, or the need for rapid response teams to be called. Our work focuses on the...

Multiscale High-Level Feature Fusion for Histopathological Image Classification.

Computational and mathematical methods in medicine
Histopathological image classification is one of the most important steps for disease diagnosis. We proposed a method for multiclass histopathological image classification based on deep convolutional neural network referred to as coding network. It c...

Procalcitonin as Predictor of Bacterial Infection in Meconium Aspiration Syndrome.

American journal of perinatology
BACKGROUND: There is a lack of definite consensus on indications for initiating antibiotics in neonates with meconium aspiration syndrome (MAS), instigating researchers to search for a biomarker that can help differentiate MAS from MAS with bacterial...