BACKGROUND: Lymph node metastasis (LNM) poses a considerable threat to survival in lung adenocarcinoma. Currently, minor resection is the recommended surgical approach for small-diameter lung cancer. The accurate preoperative identification of LNM in...
The recognition of endogenous peptides by HLA class I plays a crucial role in CD8+ T cell immune responses and human adaptive cell immune. Thus, the prediction of HLA class I-peptide binding affinities is always the core issue for the research of imm...
The Journal of the Acoustical Society of America
May 1, 2025
The sweep frequency impedance (SFI) meter is an apparatus that delivers a frequency-sweeping sound into the ear canal and evaluates dynamic characteristics of the middle ear based on changes in sound pressure in the ear canal. We have renewed the SFI...
OBJECTIVES: Previous deep learning studies have not explored the synergistic effects of ROI dimensions (2D/2.5D/3D), peritumoral expansion levels (0-8 mm), and segmentation scenarios (ROI only vs. ROI original). Our study aims to evaluate the perform...
OBJECTIVES: To identify the factors associated with post-stroke depression (PSD) and develop a machine learning predictive model using a large dataset, considering sociodemographic, lifestyle, and clinical factors.
Small molecules have been playing a crucial role in drug discovery; however, some exhibit nonspecific inhibitory effects during hit screening due to the formation of colloidal aggregators. Such false positives often lead to significant research costs...
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
May 1, 2025
OBJECTIVE: To outline immune-cell infiltration and identify diagnostic genes for atherosclerosis (AS) to better understand the potential molecular processes involved in AS development.
BACKGROUND: Accurate diagnosis of neuroendocrine neoplasms (NENs) is challenging, especially in poorly differentiated neuroendocrine carcinomas (NECs). This study was aimed to search the best or best combination of neuroendocrine markers in the diagn...
Journal of the American Medical Informatics Association : JAMIA
May 1, 2025
OBJECTIVES: To determine the extent to which current large language models (LLMs) can serve as substitutes for traditional machine learning (ML) as clinical predictors using data from electronic health records (EHRs), we investigated various factors ...
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