AIMC Topic: Sensitivity and Specificity

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A European multicenter study on the analytical performance of the VERIS HBV assay.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec 19, 2017
BACKGROUND: Hepatitis B viral load monitoring is an essential part of managing patients with chronic Hepatits B infection. Beckman Coulter has developed the VERIS HBV Assay for use on the fully automated Beckman Coulter DxN VERIS Molecular Diagnostic...
Limit of Detection RNA, Viral Humans Hepatitis B virus Hepatitis B Genotype Molecular Diagnostic Techniques Europe Automation, Laboratory Sensitivity and Specificity Viral Load Real-Time Polymerase Chain Reaction
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Epileptic Seizures Prediction Using Machine Learning Methods.

Computational and mathematical methods in medicine Dec 19, 2017
Epileptic seizures occur due to disorder in brain functionality which can affect patient's health. Prediction of epileptic seizures before the beginning of the onset is quite useful for preventing the seizure by medication. Machine learning technique...
Electroencephalography Epilepsy Seizures Signal Processing, Computer-Assisted Sensitivity and Specificity Diagnosis, Computer-Assisted Support Vector Machine Models, Statistical Humans Algorithms Brain Reproducibility of Results
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Artificial intelligence in fracture detection: transfer learning from deep convolutional neural networks.

Clinical radiology Dec 18, 2017
AIM: To identify the extent to which transfer learning from deep convolutional neural networks (CNNs), pre-trained on non-medical images, can be used for automated fracture detection on plain radiographs.
Humans Neural Networks, Computer Fractures, Bone Diagnosis, Differential Radiographic Image Interpretation, Computer-Assisted Artificial Intelligence Machine Learning Sensitivity and Specificity Deep Learning
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Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to Be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort.

The Journal of molecular diagnostics : JMD Dec 18, 2017
Tuberculosis (TB) diagnosis among sputum-scarce patients is time consuming. Thus, a nonsputum diagnostic alternative is urgently needed. The Mycobacterium tuberculosis-specific transrenal (Tr) DNA from urine is a potential target for TB diagnostics. ...
Molecular Diagnostic Techniques DNA, Bacterial Logistic Models Universities Sputum Point-of-Care Systems Middle Aged HIV Infections Cohort Studies Diagnostic Tests, Routine Polymerase Chain Reaction Multivariate Analysis South Africa Microscopy Tuberculosis, Pulmonary Mycobacterium tuberculosis Female Risk Factors Aged Aged, 80 and over Young Adult Adult Sensitivity and Specificity Cross-Sectional Studies Male Humans Biomarkers
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Verification and large scale clinical evaluation of a national standard protocol for Salmonella spp./Shigella spp. screening using real-time PCR combined with guided culture.

Journal of microbiological methods Dec 17, 2017
Salmonella spp./Shigella spp. are often associated with food poisoning and fecal-oral transmission of acute gastroenteritis that requires strict monitoring, especially among people who would handle food and water. In 2014, the National Health and Fam...
Shigella Sensitivity and Specificity China Salmonella Time Factors Real-Time Polymerase Chain Reaction Feces Mass Screening Limit of Detection Gastroenteritis Humans Reproducibility of Results
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Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).

Clinical epigenetics Dec 15, 2017
BACKGROUND: DNA methylation has been implicated as a promising biomarker for precise cancer diagnosis. However, limited DNA methylation-based biomarkers have been described in esophageal squamous cell carcinoma (ESCC).
Pseudogenes Repressor Proteins Serine-Threonine Kinase 3 Esophageal Neoplasms CpG Islands Promoter Regions, Genetic Esophageal Squamous Cell Carcinoma Middle Aged Logistic Models Epigenesis, Genetic Databases, Genetic Sequence Analysis, DNA DNA Methylation Early Detection of Cancer Protein Serine-Threonine Kinases DNA-Binding Proteins Carcinoma, Squamous Cell Aged Sensitivity and Specificity Biomarkers, Tumor Male Humans Machine Learning Female
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The ability to predict pregnancy loss in cattle with ELISAs that detect pregnancy associated glycoproteins is antibody dependent.

Theriogenology Dec 14, 2017
The concentration of circulating pregnancy associated glycoproteins (PAGs) early in pregnancy may serve as markers to predict late embryonic mortality or fetal mortality in cattle. In this study, pregnancies were established in dairy cows, by either ...
Animals Cattle ROC Curve Enzyme-Linked Immunosorbent Assay Predictive Value of Tests Antibodies, Monoclonal Abortion, Spontaneous Embryo, Mammalian Abortion, Veterinary Sensitivity and Specificity Pregnancy Proteins
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The identification of high potential archers based on fitness and motor ability variables: A Support Vector Machine approach.

Human movement science Dec 14, 2017
Support Vector Machine (SVM) has been shown to be an effective learning algorithm for classification and prediction. However, the application of SVM for prediction and classification in specific sport has rarely been used to quantify/discriminate low...
Reproducibility of Results Young Adult Sensitivity and Specificity Male Exercise Humans Algorithms Female Predictive Value of Tests Athletic Performance Athletes Linear Models Sports Adolescent Support Vector Machine Cluster Analysis Hand Strength Models, Statistical
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Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum.

Journal of visualized experiments : JoVE Dec 13, 2017
For a biosensing platform to have clinical relevance in point-of-care (POC) settings, assay sensitivity, reproducibility, and ability to reliably monitor analytes against the background of human serum are crucial. Nanoimprinting lithography (NIL) was...
Sensitivity and Specificity Troponin T Surface Plasmon Resonance Optical Rotation Humans Biomarkers
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Machine learning techniques for breast cancer computer aided diagnosis using different image modalities: A systematic review.

Computer methods and programs in biomedicine Dec 12, 2017
BACKGROUND AND OBJECTIVE: The high incidence of breast cancer in women has increased significantly in the recent years. Physician experience of diagnosing and detecting breast cancer can be assisted by using some computerized features extraction and ...
Image Processing, Computer-Assisted Mammography Area Under Curve Positron-Emission Tomography Electronic Data Processing Female Reproducibility of Results Sensitivity and Specificity Breast Neoplasms Diagnosis, Computer-Assisted Humans Machine Learning Databases, Factual Computer Simulation
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