Sepsis is a life-threatening organ dysfunction due to a dysfunctional response to infection. Delays in diagnosis have substantial impact on survival. Herein, blood samples from 586 in-house patients with suspected sepsis are used in conjunction with ...
BACKGROUND: Major Adverse Kidney Events within 30 days (MAKE30) is an important patient-centered outcome for assessing the impact of acute kidney injury (AKI). Existing prediction models for MAKE30 are static and overlook dynamic changes in clinical ...
BACKGROUND: Sepsis-associated liver injury (SALI) is a severe complication of sepsis that contributes to increased mortality and morbidity. Early identification of SALI can improve patient outcomes; however, sepsis heterogeneity makes timely diagnosi...
Sepsis remains a leading cause of mortality in critical care settings, necessitating timely and accurate risk stratification. However, existing machine learning models for sepsis prediction often suffer from poor interpretability, limited generalizab...
Early diagnosis of bloodstream infection (BSI) is crucial for informed antibiotic use. This study developed a machine learning approach for early BSI detection using a comprehensive dataset from Rigshospitalet, Denmark (2010-2020). The dataset includ...
Studies in health technology and informatics
May 15, 2025
Explainable Artificial Intelligence (XAI) is crucial for enhancing transparency, interpretability and actionability of AI systems, particularly in healthcare. The SAD XAI Dashboard, a clinical decision support (CDS) tool for sepsis-associated deliriu...
Studies in health technology and informatics
May 15, 2025
Artificial Intelligence (AI) has significantly advanced clinical decision support systems in healthcare, particularly using Machine Learning (ML) models. However, the technical nature of current ML model documentation often leads to lack of comprehen...
BACKGROUND: Early identification of children at risk of sepsis in emergency departments (EDs) is crucial for timely treatment and improved outcomes. Existing risk scores and criteria for paediatric sepsis are not well-suited for early diagnosis in ED...
BMC medical informatics and decision making
May 14, 2025
BACKGROUND: Bloodstream Infection (BSI) is a severe systemic infectious disease that can lead to sepsis and Multiple Organ Dysfunction Syndrome (MODS), resulting in high mortality rates and posing a major public health burden globally. Early identifi...
We aimed to develop machine learning(ML) algorithms to evaluate complications of flexible ureteroscopy and laser lithotripsy(fURSL), providing a valid predictive model. 15 ML algorithms were trained on a large number fURSL data from > 6500 patients f...
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