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A multicolor multiplex lateral flow assay for high-sensitivity analyte detection using persistent luminescent nanophosphors.

Analytical methods : advancing methods and applications
Incorporating two persistent luminescent nanophosphors (PLNPs), green-emitting SrAlO:Eu,Dy (SAO) and blue-emitting (SrBa)MgSiO:Eu,Dy (SBMSO), in a single lateral flow assay (LFA) establishes a luminescence-based, multiplex point-of-need test capable ...

Ratiometric fluorescent sensing system for drug residue analysis: Highly sensitive immunosensor using dual-emission quantum dots hybrid and compact smartphone based-device.

Analytica chimica acta
Immunoassays such as the enzyme-linked immunosorbent assay (ELISA) are utilized extensively for detecting protein biomarkers and small molecules in healthcare, environmental monitoring, and food analysis. Unfortunately, the current strategies for imm...

Investigation of magnetic silica with thermoresponsive chitosan coating for drug controlled release and magnetic hyperthermia application.

Materials science & engineering. C, Materials for biological applications
In this study, a drug delivery system for chemo-hyperthermia applications is proposed and fabricated. The delivery system consists of magnetic-silica (MagSi) particles being encapsulated within a pH/thermo-responsive chitosan‑g‑N‑isopropylacrylamide ...

A novel N,N'-bis(acetylacetone)ethylenediimine functionalized silica-core shell magnetic nanosorbent for manetic dispersive solid phase extraction of copper in cereal and water samples.

Food chemistry
Determination of heavy metals at trace levels has a great deal of importance due to their undesirable effects on human life. In this study, N,N'-bis (acetyl acetone) ethylenediimine (FeO@SiO-EDN) was synthesized and applied for dispersive solid phase...

Host Cell Prediction of Exosomes Using Morphological Features on Solid Surfaces Analyzed by Machine Learning.

The journal of physical chemistry. B
Exosomes are extracellular nanovesicles released from any cells and found in any body fluid. Because exosomes exhibit information of their host cells (secreting cells), their analysis is expected to be a powerful tool for early diagnosis of cancers. ...

Functional Nanoparticles-Coated Nanomechanical Sensor Arrays for Machine Learning-Based Quantitative Odor Analysis.

ACS sensors
A sensing signal obtained by measuring an odor usually contains varied information that reflects an origin of the odor itself, while an effective approach is required to reasonably analyze informative data to derive the desired information. Herein, w...

Understanding of proton induced synaptic behaviors in three-terminal synapse device for neuromorphic systems.

Nanotechnology
In this study, we investigate a proton-based three-terminal (3-T) synapse device to realize linear weight-update and I-V linearity characteristics for neuromorphic systems. The conductance states of the 3-T synapse device can be controlled by modulat...

Profiling of Exosomal Biomarkers for Accurate Cancer Identification: Combining DNA-PAINT with Machine- Learning-Based Classification.

Small (Weinheim an der Bergstrasse, Germany)
Exosomes are endosome-derived vesicles enriched in body fluids such as urine, blood, and saliva. So far, they have been recognized as potential biomarkers for cancer diagnostics. However, the present single-variate analysis of exosomes has greatly li...

Untethered Single Cell Grippers for Active Biopsy.

Nano letters
Single cell manipulation is important in biosensing, biorobotics, and quantitative cell analysis. Although microbeads, droplets, and microrobots have been developed previously, it is still challenging to simultaneously excise, capture, and manipulate...

A Novel Method to Gently Mix and Uniformly Suspend Particulates for Automated Assays.

SLAS technology
The SpinVessel system provides a methodology using pulsed radial flow to gently mix and uniformly suspend particulates (cells, magnetic beads, silica beads, and microcarrier beads) for automated assays. SpinVessels are well suited for aliquoting on r...