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Single Photon Emission Computed Tomography Computed Tomography

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Measurement of Glomerular Filtration Rate using Quantitative SPECT/CT and Deep-learning-based Kidney Segmentation.

Scientific reports
Quantitative SPECT/CT is potentially useful for more accurate and reliable measurement of glomerular filtration rate (GFR) than conventional planar scintigraphy. However, manual drawing of a volume of interest (VOI) on renal parenchyma in CT images i...

Deep learning enables automated localization of the metastatic lymph node for thyroid cancer on I post-ablation whole-body planar scans.

Scientific reports
The accurate detection of radioactive iodine-avid lymph node (LN) metastasis on I post-ablation whole-body planar scans (RxWBSs) is important in tracking the progression of the metastatic lymph nodes (mLNs) of patients with papillary thyroid cancer (...

[Not Available].

Zeitschrift fur medizinische Physik
BACKGROUND: Currently there is an ever increasing interest in Lu-177 targeted radionuclide therapies, which target neuro-endocrine and prostate tumours. For a patient-specific treatment, an individual dosimetry based on SPECT/CT imaging is necessary....

Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Dedicated cardiac SPECT scanners with cadmium-zinc-telluride cameras have shown capabilities for shortened scan times or reduced radiation doses, as well as improved image quality. Since most dedicated scanners do not have integrated CT, image quanti...

Quantitative salivary gland SPECT/CT using deep convolutional neural networks.

Scientific reports
Quantitative single-photon emission computed tomography/computed tomography (SPECT/CT) using Tc-99m pertechnetate aids in evaluating salivary gland function. However, gland segmentation and quantitation of gland uptake is challenging. We develop a sa...

Development of attenuation correction methods using deep learning in brain-perfusion single-photon emission computed tomography.

Medical physics
PURPOSE: Computed tomography (CT)-based attenuation correction (CTAC) in single-photon emission computed tomography (SPECT) is highly accurate, but it requires hybrid SPECT/CT instruments and additional radiation exposure. To obtain attenuation corre...

Deep learning-based denoising in projection-domain and reconstruction-domain for low-dose myocardial perfusion SPECT.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: Low-dose (LD) myocardial perfusion (MP) SPECT suffers from high noise level, leading to compromised diagnostic accuracy. Here we investigated the denoising performance for MP-SPECT using a conditional generative adversarial network (cGAN)...

Deep Learning Coronary Artery Calcium Scores from SPECT/CT Attenuation Maps Improve Prediction of Major Adverse Cardiac Events.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Low-dose ungated CT attenuation correction (CTAC) scans are commonly obtained with SPECT/CT myocardial perfusion imaging. Despite the characteristically low image quality of CTAC, deep learning (DL) can potentially quantify coronary artery calcium (C...

Deep learning enhanced ultra-fast SPECT/CT bone scan in patients with suspected malignancy: quantitative assessment and clinical performance.

Physics in medicine and biology
. To evaluate the clinical performance of deep learning-enhanced ultrafast single photon emission computed tomography/computed tomography (SPECT/CT) bone scans in patients with suspected malignancy.. In this prospective study, 102 patients with poten...