Achieving state-of-the-art performance with deep neural population dynamics models requires extensive hyperparameter tuning for each dataset. AutoLFADS is a model-tuning framework that automatically produces high-performing autoencoding models on dat...
Delineating the functional organization of mesoscale cortical columnar structure is essential for understanding brain function. We have previously demonstrated a high spatial correspondence between BOLD fMRI and LFP responses to tactile stimuli in th...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Invasive brain-machine interfaces can help restore function through the control of external devices while the addition of intracortical microstimulation (ICMS) can elicit sensations of touch and help provide further benefits for individuals living wi...
Proceedings of the National Academy of Sciences of the United States of America
Jan 4, 2022
Perhaps the most recognizable sensory map in all of neuroscience is the somatosensory homunculus. Although it seems straightforward, this simple representation belies the complex link between an activation in a somatotopic map and the associated touc...
The directionality of network information flow dictates how networks process information. A central component of information processing in both biological and artificial neural networks is their ability to perform synergistic integration-a type of co...
Prosthetic arms controlled by a brain-computer interface can enable people with tetraplegia to perform functional movements. However, vision provides limited feedback because information about grasping objects is best relayed through tactile feedback...
Investigations of spatial cellular composition of tissue architectures revealed by multiplexed in situ RNA detection often rely on inaccurate cell segmentation or prior biological knowledge from complementary single-cell sequencing experiments. Here,...
OBJECTIVE: The extraction and identification of single-unit activities in intracortically recorded electric signals have a key role in basic neuroscience, but also in applied fields, like in the development of high-accuracy brain-computer interfaces....
There is an unmet need to develop robust predictive algorithms to preoperatively identify pediatric epilepsy patients who will respond to vagus nerve stimulation (VNS). Given the similarity in the neural circuitry between vagus and median nerve affer...
Behavior is controlled by complex neural networks in which neurons process thousands of inputs. However, even short spike trains evoked in a single cortical neuron were demonstrated to be sufficient to influence behavior in vivo. Specifically, irregu...