Nowadays, with the rise of artificial intelligence (AI), deep learning algorithms play an increasingly important role in various traditional fields of research. Recently, these algorithms have already spread into data analysis for Raman spectroscopy....
Lung cancer exhibits strong heterogeneity, and its early diagnosis and precise subtyping are of great importance, as they can increase the ability to deliver personalized medicines by tailoring therapy regimens. Tissue biopsy, albeit the gold standar...
Analytical and bioanalytical chemistry
Mar 29, 2025
This study proposes a rapid identification method for foodborne pathogens by combining Raman spectroscopy with explainable machine learning. Spectral data of nine common foodborne pathogens are collected using a laser confocal Raman spectrometer, and...
Liquid biopsies are an emerging, noninvasive tool for cancer diagnostics, utilizing biological fluids for molecular profiling. Nevertheless, the current methods often lack the sensitivity and specificity necessary for early detection and real-time mo...
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases worldwide, characterized by its progressive and irreversible nature. Early diagnosis is crucial for delaying disease progression and optimizing treatment strategies. Existing dia...
Unique mechanical properties of cortical bone are defined by the arrangement and ratio of its organic and inorganic constituents. This arrangement can be influenced by ageing and disease, urging the understanding of normal and deviant morphological p...
Therapeutic drug monitoring (TDM) enables the personalization of treatment regimens, enhancing efficacy in combating infectious diseases while minimizing toxicity risks and reducing the potential for pathogenic resistance. However, existing TDM techn...
Various sensing methods have been developed for food spoilage research, but in practical applications, the accuracy of these methods is frequently constrained by the limitation of single-source data and challenges in cross-validating multimodal data....
Clozapine is widely regarded as one of the most effective therapeutics for treatment-resistant schizophrenia. Despite its proven efficacy, the therapeutic use of clozapine is complicated by its narrow therapeutic index, which necessitates rapid and p...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Mar 13, 2025
Surface-enhanced Raman scattering (SERS) is an inelastic scattering phenomenon that occurs when photons interact with substances, providing detailed molecular structure information. It exhibits various advantages including high sensitivity, specifici...
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