This work reports an efficient method to detect SARS-CoV-2 antibodies in blood samples based on SERS combined with a machine learning tool. For this purpose, gold nanoparticles directly conjugated with spike protein were used in human blood samples t...
Accurate detection of cardiovascular drugs in blood is complicated by interference from serum biomolecules. This study introduces a novel surface-enhanced Raman spectroscopy (SERS) platform incorporating "molecular hooks" to capture small drug molecu...
Dynamic real-time detection of dendritic cell (DC) maturation is pivotal for accurately predicting immune system activation, assessing vaccine efficacy, and determining the effectiveness of immunotherapy. The heterogeneity of cells underscores the s...
The accurate identification of Radix Astragali holds significant scientific importance for evaluating the quality and medicinal efficacy of this herb. In this study, we introduced an efficient methodology, integrating laser induced breakdown spectros...
Surface-enhanced Raman spectroscopy (SERS) analysis based on body fluids has been widely applied in disease diagnose. Choledocholithiasis is a widespread and often recurrent digestive system disease, with limited data on factors predicting its format...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Oct 4, 2024
Cell misuse and cross-contamination pose a significant threat to the accuracy of cell research outcomes, often leading to the wasteful expenditure of time, manpower, and material resources. Consequently, the accurate identification of cell lines is p...
'Akizuki' pear ( Nakai) corky disease is a physiological disease that strongly affects the fruit quality of 'Akizuki' pear and its economic value. In this study, Raman spectroscopy was employed to develop an early diagnosis model by integrating suppo...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Sep 26, 2024
Raman spectroscopy has emerged as a highly sensitive, rapid, and label-free detection method, extensively utilized in biological research. Presently, it is frequently paired with artificial intelligence (AI) algorithms to facilitate identification an...
Analytical and bioanalytical chemistry
Sep 25, 2024
Gastric and esophageal cancers, the predominant forms of upper gastrointestinal malignancies, contribute significantly to global cancer mortality. Routine detection methods, including medical imaging, endoscopic examination, and pathological biopsy, ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Sep 23, 2024
Atherosclerosis carotid stenosis (ACS) is one of the main causes of stroke. Unfortunately, the highest number of people go to the doctor with an advanced disease or as a result of a stroke, because carotid atherosclerosis does not cause obvious sympt...
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