AIMC Topic: Spectrum Analysis, Raman

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Applications of benchtop and portable spectroscopy techniques for food quality monitoring.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Food safety and quality have become major worldwide issues. Because of their quickness, effectiveness, and non-destructive nature, spectroscopy methods are essential for guaranteeing the safety and quality of food items. These techniques include Four...

Integration of label-free surface enhanced Raman spectroscopy (SERS) of extracellular vesicles (EVs) with Raman tagged labels to enhance ovarian cancer diagnostics.

Biosensors & bioelectronics
We report a proof-of-concept diagnostic strategy that integrates multiplexed Raman-tagged antibody labeling with label-free surface-enhanced Raman spectroscopy (SERS) and machine learning (ML) to improve the detection of ovarian cancer via extracellu...

Overcoming Fluorescence Interference: "Planar Hotspot" Substrates for Vitamin B Detection with SERS.

Analytical chemistry
Surface-enhanced Raman scattering (SERS) has demonstrated remarkable potential for molecular detection due to its specificity. However, detecting fluorescent vitamin B molecules remains challenging due to fluorescence interference and weak Raman cros...

Rapid classification of bacteria by a portable Raman spectrometer and machine learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Efficient, accurate, and early identification of plant pathogens is crucial for reducing disease spread and ensuring food security. The development of rapid diagnostic methods based on Raman spectroscopy (RS) coupled with machine learning (ML) holds ...

AgNWs-COF SERS biosensor for oral cancer diagnosis based on exhaled breath and saliva.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Over recent years, surface-enhanced Raman spectroscopy (SERS) has shown its unparalleled sensitivity and molecular specificity in biomedical applications. However, noninvasive and sensitive detection of biomarkers with conventional SERS for oral canc...

Analysis of the carotenoid cycle during microbial growth by combining fluorescence imaging and deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Detection and real-time tracking of changes in the relative carotenoid content during microbial growth can be extremely challenging. Additionally, analyzing its content cycling time can also be highly difficult. In this study, Raman tweezers were emp...

Urine-based Raman markers for prostate cancer diagnosis: A machine learning approach using fingerprint and lipid spectral region.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study investigates the potential of Raman spectroscopy in distinguishing between healthy individuals and prostate cancer patients using urine samples. The Boruta algorithm was applied to Raman spectral data in two distinct wavenumber regions: 80...

Deep learning-assisted Raman spectroscopy for rapid lactic acid bacteria identification at the colony level.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
To achieve rapid and accurate identification at the colony level and improve the efficiency of colony selection, we proposed an adaptive colony Raman acquisition method based on signal-to-noise ratio screening (ACRA-SNR). This method enables in situ ...

Discrimination of Dengue Diseases in Children Using Surface-Enhanced Raman Spectroscopy Coupled with Machine Learning Approaches.

Analytical chemistry
This study introduces a novel approach to dengue diagnostics by leveraging surface-enhanced Raman spectroscopy (SERS) coupled to machine learning. This method addresses the critical need for rapid and accurate identification of dengue virus (DENV) in...

Dual-Mode SERS Lateral Flow Aptamer Assay with Machine Learning-Driven Highly Sensitive Interferon-γ Detection.

ACS synthetic biology
Interferon-γ (IFN-γ), a key pro-inflammatory cytokine, is widely recognized as a critical biomarker for diagnosing and monitoring various immune-related conditions. However, its typically low concentrations in biological fluids─at the picogram-per-mi...