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T-Lymphocytes

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Serum Concentrations of Interferon Gamma (IFN-γ) in Patients with Psoriasis: Correlation with Clinical Type and Severity of the Disease.

Medical archives (Sarajevo, Bosnia and Herzegovina)
INTRODUCTION: The etiopathogenesis of psoriasis is still unclear but there is evidence that many of cytokines released by keratinocytes and inflammatory leukocytes may contribute to the induction or persistence of the inflammatory process in psoriasi...

[Effect of Recombinant Antigen Ferritin on DC Induce Immune Response].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVE: To explore the immunoreaction against protoscolex infection by the recombinant ferritin of echinococcus granulosus (rEg.ferritin) immunized mice.

Using OWL reasoning to support the generation of novel gene sets for enrichment analysis.

Journal of biomedical semantics
BACKGROUND: The Gene Ontology (GO) consists of over 40,000 terms for biological processes, cell components and gene product activities linked into a graph structure by over 90,000 relationships. It has been used to annotate the functions and cellular...

New tools for MHC research from machine learning and predictive algorithms to the tumour immunopeptidome.

Immunology
At a time when immunology seeks to progress ever more rapidly from characterization of a microbial or tumour antigen to the immune correlates that may define protective T-cell immunity, there is a need for robust tools to enable accurate predictions ...

Towards the development of robot immune system: A combined approach involving innate immune cells and T-lymphocytes.

Bio Systems
Mobile robots in uncertain and unstructuredenvironments frequently encounter faults. Therefore, an effective fault detection and recovery mechanism is required. One can possibly investigate natural systems to seek inspiration to develop systems that ...

Diagnosis of T-cell-mediated kidney rejection in formalin-fixed, paraffin-embedded tissues using RNA-Seq-based machine learning algorithms.

Human pathology
Molecular diagnosis is being increasingly used in transplant pathology to render more objective and quantitative determinations that also provide mechanistic and prognostic insights. This study performed RNA-Seq on biopsies from kidneys with stable f...

Cellular frustration algorithms for anomaly detection applications.

PloS one
Cellular frustrated models have been developed to describe how the adaptive immune system works. They are composed by independent agents that continuously pair and unpair depending on the information that one sub-set of these agents display. The emer...

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space.

Frontiers in immunology
Immunodominant T cell epitopes preferentially targeted in multiple individuals are the critical element of successful vaccines and targeted immunotherapies. However, the underlying principles of this "convergence" of adaptive immunity among different...

Generating automated kidney transplant biopsy reports combining molecular measurements with ensembles of machine learning classifiers.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
We previously reported a system for assessing rejection in kidney transplant biopsies using microarray-based gene expression data, the Molecular Microscope Diagnostic System (MMDx). The present study was designed to optimize the accuracy and stabilit...